(2018)
Facile assembly and fluorescence-based screening method for heterologous expression of biosynthetic pathways in fungi.
Metab Eng 48,
44-51.
Curriculum vitae
Main Research Areas
- Quinone synthetases and related enzymes
- Polyketide synthases of basidiomycetes
- Biosynthesis of psilocybin
- Natural products of the genus Psilocybe
Professional Career
| 2014- | Full Professor for Pharmaceutical Microbiology, FSU Jena and HKI Jena |
| 2009-2014 | Associate Professor for Pharmaceutical Biology, FSU Jena and head of the associated department Pharmaceutical Biology at the HKI Jena |
| 2007-2009 | Assistant Professor (tenure track) University of Minnesota, Saint Paul, MN, USA |
| 2008 | Habilitation in Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University Freiburg |
| 2004-2007 | Junior Group Leader, Institute for Pharmacy, Albert-Ludwigs-University, Freiburg |
| 2002-2004 | Postdoc, University of Wisconsin, Madison, WI, USA (DFG-fellowship) |
| 2002 | Dr. rer. nat., Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University, Freiburg |
| 1998 | Diploma in biology at the Eberhard-Karls-University, Tübingen |
Awards · Appointments · Scientific Activities
| Since 2020 | Head of the Institute for Pharmacy, FSU Jena |
| 2016-2019 | Dean for Study Affairs in the Faculty of Biology and Pharmacy, FSU Jena |
| 2013-2016 | Scientific advisory board, Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM). |
Publications
(2018)
Dissimilar pigment regulation in Serpula lacrymans and Paxillus involutus during interkingdom interactions.
Microbiology 164(1),
65-77.
(2018)
Analysis of basidiomycete pigments in situ by Raman spectroscopy.
J Biophoton 11(6),
e201700369.
(2017)
Structure of ralsolamycin, the inter-kingdom morphogen of the crop plant pathogen Ralstonia solanacearum GMI1000.
Org Lett 19(18),
4868-4871.
(2017)
Biochemical and genetic basis of orsellinic acid biosynthesis and prenylation in a stereaceous basidiomycete.
Fungal Genet Biol 98,
12-19.
(2017)
A highly conserved basidiomycete peptide synthetase produces a trimeric hydroxamate siderophore.
Appl Environ Microbiol 83(21),
e01478.
(2017)
Induced chemical defense of a mushroom by a double-bond-shifting polyene synthase.
Angew Chem Int Ed 56(21),
5937-5941.
(2017)
Enzymatic synthesis of psilocybin.
Angew Chem Int Ed 56(40),
12352-12355.
(2017)
Identification of N-Methyl-4-hydroxytryptamine (Norpsilocin) as a Psilocybe natural product.
J Nat Prod 80(10),
2835-2838.
(2017)
Fungal variegatic acid and extracellular polysaccharides promote the site specific generation of reactive oxygen species.
J Ind Microbiol Biotechnol 44,
329-338.
