(2017)
Fungal variegatic acid and extracellular polysaccharides promote the site specific generation of reactive oxygen species
J Ind Microbiol Biotechnol 44,
329-338.
Dirk Hoffmeister
Pharmaceutical Microbiology · Head +49 3641 9-49850 dirk.hoffmeister@leibniz-hki.deCurriculum vitae
Main Research Areas
- Quinone synthetases and related enzymes
- Polyketide synthases of basidiomycetes
- Biosynthesis of psilocybin
- Natural products of the genus Psilocybe
Professional Career
| 2014- | Full Professor for Pharmaceutical Microbiology, FSU Jena and HKI Jena |
| 2009-2014 | Associate Professor for Pharmaceutical Biology, FSU Jena and head of the associated department Pharmaceutical Biology at the HKI Jena |
| 2007-2009 | Assistant Professor (tenure track) University of Minnesota, Saint Paul, MN, USA |
| 2008 | Habilitation in Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University Freiburg |
| 2004-2007 | Junior Group Leader, Institute for Pharmacy, Albert-Ludwigs-University, Freiburg |
| 2002-2004 | Postdoc, University of Wisconsin, Madison, WI, USA (DFG-fellowship) |
| 2002 | Dr. rer. nat., Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University, Freiburg |
| 1998 | Diploma in biology at the Eberhard-Karls-University, Tübingen |
Awards · Appointments · Scientific Activities
| Since 2020 | Head of the Institute for Pharmacy, FSU Jena |
| 2016-2019 | Dean for Study Affairs in the Faculty of Biology and Pharmacy, FSU Jena |
| 2013-2016 | Scientific advisory board, Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM). |
Publications
(2016)
Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus.
Nat Chem Biol 12,
419-424.
(2016)
A non-canonical peptide synthetase adenylates 3-methyl-2-oxovaleric acid for auriculamide biosynthesis
Beilstein J Org Chem 12,
2766-2770.
(2016)
Active-Site Engineering Expands the Substrate Profile of the Basidiomycete L-Tryptophan Decarboxylase CsTDC.
ChemBioChem 17,
132-136.
(2016)
An Iterative O-Methyltransferase Catalyzes 1,11-Dimethylation of Aspergillus fumigatus Fumaric Acid Amides.
ChemBioChem 17,
1813-1817.
(2016)
Globally distributed root endophyte Phialocephala subalpina links pathogenic and saprophytic lifestyles
BMC Genomics 17,
1015.
(2016)
Unexpected metabolic versatility in a combined fungal fomannoxin/vibralactone biosynthesis.
J. Nat. Prod. 79,
1407-1414.
(2016)
Ectomycorrhizal fungi decompose soil organic matter using oxidative mechanisms adapted from saprotrophic ancestors.
New Phytol 209,
1705-1719.
(2016)
Involutin is a Fe3+ reductant Secreted by the Ectomycorrhizal Fungus Paxillus involutus during Fenton-based Decomposition of Organic Matter.
Appl Environ Microbiol 81,
8427-8433.
(2016)
Bacteria induce pigment formation in the basidiomycete Serpula lacrymans.
Environ Microbiol 18,
5218-5227.
