Pharmaceutical Microbiology

Büttner H, Rassbach J, Schultz C, Popp J, Gressler M, Hertweck C (2024) Beneficial soil fungus kills predatory nematodes with dehydropeptides translocating into the animal gut. J Am Chem Soc 146(50), 34702-34710.

Dellière S, Chauvin C, Wong SSW, Gressler M, Possetti V, Parente R, Fontaine T, Krüger T, Kniemeyer O, Bayry J, Carvalho A, Brakhage AA, Inforzato A, Latgé JP, Aimanianda V (2024) Interplay between host humoral pattern recognition molecules controls undue immuneresponses against Aspergillus fumigatus. Nat Commun 15(1), 6966.

Dörner S, Trottmann F, Jordan P, Bartels B, Rogge K, Werz O, Hertweck C, Hoffmeister D (2024) The fatal mushroom neurotoxin muscarine is released from a harmless phosphorylated precursor upon cellular injury. Angew Chem Int Ed 63(52), e202417220.

Hudspeth J, Rogge K, Dörner S, Müll M, Hoffmeister D, Rupp B, Werten S (2024) Methyl transfer in psilocybin biosynthesis. Nat Commun 15(1), 2709.

Hudspeth JD, Rogge K, Wagner T, Müll M, Hoffmeister D, Rupp B, Werten S (2024) The second methylation in Psilocybin biosynthesis is enabled by a hydrogen bonding network extending into the secondary sphere surrounding the methyltransferase active site. ChemBioChem 25(23), e202400497.

Janevska S^*#, Weiser S^*, Huang Y, Lin J, Hoefgen S, Jojić K, Barber AE, Schäfer T, Fricke J, Hoffmeister D, Regestein L, Valiante V, Kufs JE^# (2024) Optimized psilocybin production in tryptophan catabolism-repressed fungi. Microb Biotechnol 17(11), e70039.

Löhr NA, Platz L, Hoffmeister D, Müller M (2024) From the forest floor to the lab: insights into the diversity and complexity of mushroom polyketide synthases. Curr Opin Chem Biol 82, 102510. (Review)

Platz L, Löhr NA, Gerkens MP, Eisen F, Bär C, Braun K, Fessner N, Hüttel W, Hoffmeister D, Müller M (2024) Regioselective oxidative phenol coupling by a mushroom unspecific peroxygenase. Angew Chem Int Ed 63(42), e202407425.

Rogge K, Wagner T, Hoffmeister D, Rupp B, Werten S (2024) Substrate recognition by the 4-hydroxytryptamine kinase PsiK in Psilocybin biosynthesis. FEBS Letters [Accepted]

Schäfer T, Haun F, Gressler M, Spiteller P, Hoffmeister D (2024) Parallel evolution of Asco- and Basidiomycete O-Prenyltransferases. J Nat Prod 87(3), 576-582.