Publications

Hoffmeister D, Thorson JS (2004) Mechanistic implications of Escherichia coli galactokinase structure-based engineering. Chembiochem 5, 989-992.
Hoffmeister D, Weber M, Dräger G, Ichinose K, Dürr C, Bechthold A (2004) Rational saccharide extension by using the natural product glycosyltransferase LanGT4. Chembiochem 5, 369-371.
Thorson JS, Barton WA, Hoffmeister D, Albermann C, Nikolov DB (2004) Structure-based enzyme engineering and its impact on in vitro glycorandomization. Chembiochem 5, 16-25.
Hoffmeister D, Dräger G, Ichinose K, Rohr J, Bechthold A (2003) The C-Glycosyltransferase UrdGT2 is unselective toward d- and l-configured nucleotide-bound rhodinoses. J Am Chem Soc 125, 4678-4679.
Hoffmeister D, Yang J, Liu L, Thorson JS (2003) Creation of the first anomeric D/L-sugar kinase by means of directed evolution. Proc Natl Acad Sci U S A 100, 13184-13189.
Pelzer S, Hoffmeister D, Merfort I, Bechthold A (2003) Procaryotic and eucaryotic cells in biotech production In: Kayser O, Müller R. H. (eds.) Pharmaceutical Biotechnology, Drug Discovery and Clinical Applications pp. 9-33. Wiley-Blackwell.
Rebets Y, Ostash B, Luzhetskyy A, Hoffmeister D, Brana A, Mendez C, Salas JA, Bechthold A, Fedorenko V (2003) Production of landomycins in Streptomyces globisporus 1912 and S cyanogenus S136 is regulated by genes encoding putative transcriptional activators. FEMS Microbiol Lett 222, 149-153.
Rix U, Remsing LL, Hoffmeister D, Bechthold A, Rohr J (2003) Urdamycin L: a novel metabolic shunt product that provides evidence for the role of the urdM gene in the urdamycin A biosynthetic pathway of Streptomyces fradiae TU 2717. Chembiochem 4, 109-111.
Hoffmeister D, Wilkinson B, Foster G, Sidebottom PJ, Ichinose K, Bechthold A (2002) Engineered urdamycin glycosyltransferases are broadened and altered in substrate specificity. Chem Biol 9, 287-295.
Hoffmeister D, Ichinose K, Bechthold A (2001) Two sequence elements of glycosyltransferases involved in urdamycin biosynthesis are responsible for substrate specificity and enzymatic activity. Chem Biol 8, 557-567.