Elena Seibel

Elena Seibel

Chemical Biology of Microbe-Host Interactions · PhD student +49 3641 532-1226 elena.seibel@leibniz-hki.de

Curriculum vitae

Main Research Areas
  • Elucidation of biosynthetic pathways
  • Analysis of microbial interactions
  • identification of signal molecules mediating insect-fungus-bacteria interactions
Professional Career

since 2018 PhD student(ANR-Projekt: „BiBiMac -  Biomimetic synthesis, biosynthetic pathway engineering and structure studies of unique glycosylated macrolactams”)
2013 – 2017 M. Sc. Chemical Biology, FSU Jena    
2015 Erasmus study abroad, Faculdade de Ciências da Universidade de Lisboa
2010 – 2013 B. Sc. Biochemie/ Molekularbiologie, Fakultät der Biowissenschaften, FSU Jena
Awards · Appointments · Scientific Activities

2016 research stay: D. K. Zabolotny Institute for Mikrobiology and Virology Kiew, Ukraine
2015 research stay: Hovione FarmaCiência S.A., Sete Casas, Loures, Portugal
2014 Fresearch stay: Instiute for Biology and Zoology, Universidade Paulista, Câmpus Ilha Solteira
2012 -
2014		 student assistant at the Max-Planck-Institut for Chemical Ecology (MPI-CE), Jena
2011 -
2013		 teaching assistent at the Institute for Ecology, Faculty of Biosciences, FSU Jena

Topics

Publications

Fricke J, Schalk F, Kreuzenbeck NB, Seibel E, Hoffmann J, Dittmann G, Conlon BH, Guo H, Wilhelm de Beer Z, Vassão DG, Gleixner G, Poulsen M, Beemelmanns C (2023) Adaptations of Pseudoxylaria towards a comb-associated lifestyle in fungus-farming termite colonies. ISME J 17(5), 733-747.
Details
PubMed Open Access PDF Paper
Seibel E, Um S, Dayras M, Bodawatta KH, de Kruijff M, Jønsson KA, Poulsen M, Kim KH, Beemelmanns C (2023) Genome mining for macrolactam-encoding gene clusters allowed for the network-guided isolation of β-amino acid-containing cyclic derivatives and heterologous production of ciromicin A. Commun Chem 6(1), 257.
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PubMed
Guo H, Daniel JM, Seibel E, Burkhardt I, Conlon BH, Görls H, Vassão DG, Dickschat JS, Poulsen M, Beemelmanns C (2022) Insights into the metabolomic capacity of podaxis and isolation of podaxisterols A-D, ergosterol derivatives carrying nitrosyl cyanide-derived modifications. J Nat Prod 85(9), 2159-2167.
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PubMed Open Access
Kreuzenbeck NB, Seibel E, Schwitalla JW, Fricke J, Conlon BH, Schmidt S, Hammerbacher A, Köllner TG, Poulsen M, Hoffmeister D, Beemelmanns C (2022) Comparative genomic and metabolomic analysis of Termitomyces species provides insights into the terpenome of the fungal cultivar and the characteristic odor of the fungus garden of Macrotermes natalensis termites. mSystems 7(1), e0121421.
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PubMed Open Access PDF Paper
Manivannan A, Israni B, Luck K, Götz M, Seibel E, Easson MLAE, Kirsch R, Reichelt M, Stein B, Winter S, Gershenzon J, Vassão DG (2021) Identification of a sulfatase that detoxifies glucosinolates in the phloem-feeding insect Bemisia tabaci and prefers indolic glucosinolates. Front Plant Sci 12, 671286.
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PubMed Open Access PDF Paper
Sinotte VM, Conlon BH, Seibel E, Schwitalla JW, de Beer ZW, Poulsen M, Bos N (2021) Female-biased sex allocation and lack of inbreeding avoidance in Cubitermes termites. Ecol Evol 11(10), 5598-5605.
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PubMed Open Access PDF Paper
Um S, Seibel E, Schalk F, Balluf S, Beemelmanns C (2021) Targeted isolation of saalfelduracin B-D from Amycolatopsis saalfeldensis using LC-MS/MS-based molecular networking. J Nat Prod 84(4), 1002-1011.
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PubMed Open Access
Hubert P, Seibel E, Beemelmanns C, Campagne JM, de Figueiredo RM (2020) Stereoselective construction of (E,Z)-1,3-dienes and its application in natural product synthesis. Adv Synth Catal 362(24), 5532-5575. (Review)
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Israni B, Wouters FC, Luck K, Seibel E, Ahn SJ, Paetz C, Reinert M, Vogel H, Erb M, Heckel DG, Gershenzon J, Vassão DG (2020) The Fall Armyworm Spodoptera frugiperda Utilizes Specific UDP-Glycosyltransferases to Inactivate Maize Defensive Benzoxazinoids. Front Physiol 11, 604754.
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PubMed