(2024)
Interplay between host humoral pattern recognition molecules controls undue immuneresponses against Aspergillus fumigatus.
Nat Commun 15(1),
6966.
Curriculum vitae
Main Research Areas
- Biochemical and genetic basis of natural product biosynthesis of basal fungi (early-diverging fungi, especially mucoromycetes und zoopagomycetes)
- pharmaceutical application and ecological significance of fungal natural products
- alternative, non-canonical strategies of fungal natural product biosynthesis
Professional Career
| 2017-2024 | State doctorate (Habilitation) in pharmaceutical microbiology at the Friedrich-Schiller-University Jena, Germany |
| 2015-2017 | Postdoctoral, Institute Pasteur, Paris, France |
| 2009-2015 | Doctoral thesis (Dr. rer. nat.) in biochemistry at the Friedrich-Schiller-University Jena and the Hans-Knöll-Institute, Jena, Germany |
| 2003-2009 | Diploma in biochemistry/molecular biology at the Friedrich-Schiller-University Jena, Germany |
Publications
(2024)
Parallel evolution of Asco- and Basidiomycete O-Prenyltransferases.
J Nat Prod 87(3),
576-582.
(2023)
A genetic tool to express long fungal biosynthetic genes.
Fungal Biol Biotechnol 10(1),
4.
(2023)
Basidiomycete non-reducing polyketide synthases function independently of SAT domains.
Fungal Biol Biotechnol 10(1),
17.
(2023)
Non-canonical two-step biosynthesis of anti-oomycete indole alkaloids in Kickxellales.
Fungal Biol Biotechnol 1010(1),
19.
(2023)
Insecticidal cyclodepsitetrapeptides from Mortierella alpina.
J Nat Prod 86(7),
1715-1722.
(2023)
A "Magic Mushroom" multi-product sesquiterpene synthase.
ChemBioChem 24(21),
e202300511.
(2023)
Bifurcate evolution of quinone synthetases in basidiomycetes.
Fungal Biol Biotechnol 10(1),
14.
(2023)
A mushroom P450-monooxygenase enables regio- and stereoselective biocatalytic synthesis of epoxycyclohexenones.
Angew Chem Intl Ed 62(49),
e202313817.
(2022)
Genetic survey of Psilocybe natural products.
ChemBioChem 23(14),
e202200249.
