Dr. Felix Trottmann

Alumni

Publications

Dumjahn L, Wein P, Molloy EM, Scherlach K, Trottmann F, Meisinger P, Judd LM, Pidot SJ, Stinear TP, Richter I, Hertweck C (2025) Dual-use virulence factors of the opportunistic pathogen Chromobacterium haemolyticum mediate haemolysis and colonization. bioRxiv 16(5), e0360524.
Dumjahn L, Wein P, Molloy EM, Scherlach K, Trottmann F, Meisinger PR, Judd LM, Pidot SJ, Stinear TP, Richter I, Hertweck C (2025) Dual-use virulence factors of the opportunistic pathogen Chromobacterium haemolyticum mediate hemolysis and colonization. mBio 16(5), e0360524.
Fiedler J, Dumjahn L, Ishida-Ito M, Trottmann F, Ishida K, Hertweck C (2025) Thiotemplated polyketide chain fusion and reductive cyclization build the reactive butenolide core of malleicyprol. Angew Chem Int Ed 64(31), e202504485.
Zhang S, Schlabach K, Pérez Carrillo VH, Ibrahim A, Nayem S, Komor A, Mukherji R, Chowdhury S, Reimer L, Trottmann F, Vlot AC, Hertweck C, Hellmich UA, Stallforth P (2025) A chemical radar allows bacteria to detect and kill predators. Cell 188(9), 2495-2504.
Dörner S, Trottmann F, Jordan P, Bartels B, Rogge K, Werz O, Hertweck C, Hoffmeister D (2024) The fatal mushroom neurotoxin muscarine is released from a harmless phosphorylated precursor upon cellular injury. Angew Chem Int Ed 63(52), e202417220.
Ehinger FJ, Scherlach K, Trottmann F, Fiedler J, Richter I, Hertweck C (2024) A catch-release strategy for the genomics-driven discovery of antiproliferative furan-functionalized peptides. Angew Chem Int Ed 64(11), e202421760.
Fiedler J, Trottmann F, Ishida K, Mie II, Hertweck C (2024) Direct a-hydroxy acid loading onto a bacterial thiotemplate assembly line via a multienzyme gateway. Angew Chem Int Ed 63(30), e202405165.
Kries H, Trottmann F, Hertweck C (2024) Novel biocatalysts from specialized metabolism. Angew Chem Int Ed 63(4), e202309284. (Review)
Little RF, Trottmann F, Hashizume H, Preissler M, Unger S, Sawa R, Kries H, Pidot S, Igarashi M, Hertweck C (2024) Analysis of the valgamicin biosynthetic pathway reveals a general mechanism for cyclopropanol formation across diverse natural product scaffolds. ACS Chem Biol 19(3), 660-668.
Schäfer E, Seibold PS, Bartram S, Trottmann F, Hänsch V, Gressler M, Chadeayne A, Hertweck C, O'Connor S, Hoffmeister D (2023) A "Magic Mushroom" multi-product sesquiterpene synthase. ChemBioChem 24(21), e202300511.