Curriculum vitae

Main Research Areas
  • Biochemical and genetic basis of fungal natural product biosyntheses
  • Natural products of basidiomycetes and Ralstonia solanacearum
  • Microbial nonribosomal peptide synthetases
Professional Career
2014- Full Professor for Pharmaceutical Microbiology, FSU Jena and HKI Jena
2009-2014 Associate Professor for Pharmaceutical Biology, FSU Jena and head of the associated department Pharmaceutical Biology at the HKI Jena
2007-2009 Assistant professor (tenure track) University of Minnesota, Saint Paul, MN, USA
2008 Habilitation in Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University Freiburg
2004-2007 Research assistant, Institute for Pharmacy, Albert-Ludwigs-University, Freiburg
2002-2004 Postdoc, University of Wisconsin, Madison, WI, USA (DFG-fellowship)
2002 Dr. rer. nat., Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University, Freiburg
1998 Diploma in biology at the Eberhard-Karls-University, Tübingen
Awards · Appointments · Scientific Activities
Since 2016 Dean for Study Affairs in the Faculty of Biology and Pharmacy, FSU Jena
2013-2016 Scientific advisory board, Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM).
Since 2011 Member of the editorial board of various journals

Publications

Dörfer M, Gressler, M, Hoffmeister D (2019) Diversity and bioactivity of Armillaria sesquiterpene aryl ester natural products. Mycol Prog 18(8), 1027-1037.
Dörfer M, Heine D, König S, Gore S, Werz O, Hertweck C, Gressler M, Hoffmeister D (2019) Melleolides impact fungal translation via elongation factor 2. Org Biomol Chem 17(19), 4906-4916.
Fricke J, Lenz C, Wick J, Blei F, Hoffmeister D (2019) Production options for psilocybin - The making of the magic. Chem Eur J 25(4), 897-903. (Review)
Fricke J, Sherwood A, Kargbo R, Orry A, Blei F, Naschberger A, Rupp B, Hoffmeister D (2019) Enzymatic route toward 6-methylated baeocystin and psilocybin. ChemBioChem 20(22), 2824-2829.
König S, Romp E, Krauth V, Rühl M, Dörfer M, Liening S, Hoffmann B, Häfner AK, Steinhilber D, Karas M, Garscha U, Hoffmeister D, Werz O (2019) Melleolides from honey mushroom inhibit 5-lipoxygenase via Cys159. Cell Chem Biol 26(1), 60-70.e4.
Blei F, Baldeweg F, Fricke J, Hoffmeister D (2018) Biocatalytic production of psilocybin and derivatives in tryptophan synthase-enhanced reactions. Chem Eur J 24(40), 10028-10031.
Blei F, Fricke J, Wick J, Slot JC, Hoffmeister D (2018) Iterative L-tryptophan methylation in Psilocybe evolved by sub-domain duplication. ChemBioChem [Accepted]
Brandenburger E, Braga D, Kombrink A, Lackner G, Gressler J, Künzler M, Hoffmeister D (2018) Multi-genome analysis identifies functional and phylogenetic diversity of basidiomycete adenylate-forming reductases. Fungal Genet Biol 112, 55-63.
Held BW, Hoffmeister D, Blanchette RA (2018) Occurrence of european tar spot (Rhytisma acerinum) on norway maple causing severe infections in Minnesota. Plant Disease 102, 12.
Hoefgen S, Lin J, Fricke J, Stroe MC, Mattern DJ, Kufs JE, Hortschansky P, Brakhage AA, Hoffmeister D, Valiante V (2018) Facile assembly and fluorescence-based screening method for heterologous expression of biosynthetic pathways in fungi. Metab Eng 48, 44-51.