Curriculum vitae

Main Research Areas
  • Biochemical and genetic basis of fungal natural product biosyntheses
  • Natural products of basidiomycetes and Ralstonia solanacearum
  • Microbial nonribosomal peptide synthetases
Professional Career
2014- Full Professor for Pharmaceutical Microbiology, FSU Jena and HKI Jena
2009-2014 Associate Professor for Pharmaceutical Biology, FSU Jena and head of the associated department Pharmaceutical Biology at the HKI Jena
2007-2009 Assistant professor (tenure track) University of Minnesota, Saint Paul, MN, USA
2008 Habilitation in Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University Freiburg
2004-2007 Research assistant, Institute for Pharmacy, Albert-Ludwigs-University, Freiburg
2002-2004 Postdoc, University of Wisconsin, Madison, WI, USA (DFG-fellowship)
2002 Dr. rer. nat., Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University, Freiburg
1998 Diploma in biology at the Eberhard-Karls-University, Tübingen
Awards · Appointments · Scientific Activities
Since 2016 Dean for Study Affairs in the Faculty of Biology and Pharmacy, FSU Jena
2013-2016 Scientific advisory board, Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM).
Since 2011 Member of the editorial board of various journals

Publications

Kalb D, Heinekamp T, Lackner G, Scharf DH, Dahse HM, Brakhage AA, Hoffmeister D (2015) Genetic engineering activates biosynthesis of aromatic fumaric acid amides in the human pathogen Aspergillus fumigatus. Appl Environ Microbiol 81, 1594-1600.
Kalb D, Lackner G, Rappe M, Hoffmeister D (2015) Activity of α-aminoadipate reductase depends on the N-terminally extending domain. Chembiochem 16, 1426-1430.
Karlsson M, Durling MB, Choi J, Kosawang C, Lackner G, Tzelepis GD, Nygren K, Dubey MK, Kamou N, Levasseur A, Zapparata A, Wang J, Amby DB, Jensen B, Sarrocco S, Panteris E, Lagopodi AL, Pöggeler S, Vannacci G, Collinge DB, Hoffmeister D, Henrissat B, Lee YH, Jensen DF (2015) Insights on the Evolution of Mycoparasitism from the Genome of Clonostachys rosea. Genome Biol Evol 7, 465-480.
Stadler M, Hoffmeister D (2015) Fungal natural products-the mushroom perspective. Front Microbiol 6, 127.
Bohnert M, Nützmann HW, Schroeckh V, Horn F, Dahse HM, Brakhage AA, Hoffmeister D (2014) Cytotoxic and antifungal activities of melleolide antibiotics follow dissimilar structure-activity relationships. Phytochemistry 105, 101-108.
Bohnert M, Scherer O, Wiechmann K, König S, Dahse HM, Hoffmeister D, Werz O (2014) Melleolides induce rapid cell death in human primary monocytes and cancer cells. Bioorg Med Chem 22, 3856-3861.
Chankhamjon P, Boettger-Schmidt D, Scherlach K, Urbansky B, Lackner G, Kalb D, Dahse HM, Hoffmeister D, Hertweck C (2014) Biosynthesis of the Halogenated Mycotoxin Aspirochlorine in Koji Mold Involves a Cryptic Amino Acid Conversion. Angew Chem Int Ed Engl 53, 13409-13413.
Hori C, Ishida T, Igarashi K, Samejima M, Suzuki H, Master E, Ferreira P, Ruiz-Dueñas FJ, Held B, Canessa P, Larrondo LF, Schmoll M, Druzhinina IS, Kubicek CP, Gaskell JA, Kersten P, St John F, Glasner J, Sabat G, Splinter BonDurant S, Syed K, Yadav J, Mgbeahuruike AC, Kovalchuk A, Asiegbu FO, Lackner G, Hoffmeister D, Rencoret J, Gutiérrez A, Sun H, Lindquist E, Barry K, Riley R, Grigoriev IV, Henrissat B, Kües U, Berka RM, Martínez AT, Covert SF, Blanchette RA, Cullen D (2014) Analysis of the Phlebiopsis gigantea Genome, Transcriptome and Secretome Provides Insight into Its Pioneer Colonization Strategies of Wood. PLOS Genet 10, e1004759.
Kalb D, Lackner G, Hoffmeister D (2014) Functional and phylogenetic divergence of fungal adenylate-forming reductases. Appl Environ Microbiol 80, 6175-6183.
Sasso S, Shelest E, Hoffmeister D (2014) Comments on the distribution and phylogeny of type I polyketide synthases and nonribosomal peptide synthetases in eukaryotes. Proc Natl Acad Sci U S A 111, E3946.