(2013)
The fusarin analogue NG-391 impairs transcription in K-562 leukemia cells
Phytochemistry Letters 6,
189-192.
Dirk Hoffmeister
Pharmaceutical Microbiology · Head +49 3641 9-49850 dirk.hoffmeister@leibniz-hki.deCurriculum vitae
Main Research Areas
- Biochemical and genetic basis of fungal natural product biosyntheses
- Natural products of basidiomycetes and Ralstonia solanacearum
- Microbial nonribosomal peptide synthetases
Professional Career
2014- | Full Professor for Pharmaceutical Microbiology, FSU Jena and HKI Jena |
2009-2014 | Associate Professor for Pharmaceutical Biology, FSU Jena and head of the associated department Pharmaceutical Biology at the HKI Jena |
2007-2009 | Assistant Professor (tenure track) University of Minnesota, Saint Paul, MN, USA |
2008 | Habilitation in Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University Freiburg |
2004-2007 | Junior Group Leader, Institute for Pharmacy, Albert-Ludwigs-University, Freiburg |
2002-2004 | Postdoc, University of Wisconsin, Madison, WI, USA (DFG-fellowship) |
2002 | Dr. rer. nat., Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University, Freiburg |
1998 | Diploma in biology at the Eberhard-Karls-University, Tübingen |
Awards · Appointments · Scientific Activities
Since 2020 | Head of the Institute for Pharmacy, FSU Jena |
2016-2019 | Dean for Study Affairs in the Faculty of Biology and Pharmacy, FSU Jena |
2013-2016 | Scientific advisory board, Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM). |
Publications
(2013)
A gene cluster responsible for biosynthesis of phomenoic acid in the plant pathogenic fungus, Leptosphaeria maculans.
Fungal Genet Biol 53,
50-58.
(2013)
Homologous NRPS-like gene clusters mediate redundant small-molecule biosynthesis in Aspergillus flavus.
Angew Chem Int Ed Engl 52,
1590-1594.
(2013)
An iterative type I polyketide synthase initiates the biosynthesis of the antimycoplasma agent micacocidin.
Chem Biol 20,
764-771.
(2013)
Fungal peptide synthetases – an update on functions and specificity signatures
Fungal Biology Reviews 27,
43-50.
(2013)
Assembly of melleolide antibiotics involves a polyketide synthase with cross-coupling activity.
Chem Biol 20,
1101-1106.
(2013)
Ralfuranone thioether production by the plant pathogen Ralstonia solanacearum.
Chembiochem 14,
2169-2178.
(2013)
Bimodular peptide synthetase SidE produces fumarylalanine in the human pathogen Aspergillus fumigatus.
Appl Environ Microbiol 79,
6670-6676.
(2012)
Comparative genomics of Ceriporiopsis subvermispora and Phanerochaete chrysosporium provide insight into selective ligninolysis.
Proc Natl Acad Sci U S A 109,
5458-5463.
(2012)
Genome mining reveals the evolutionary origin and biosynthetic potential of basidiomycete polyketide synthases.
Fungal Genet Biol 49,
996-991003.