Abstract
Recently, we have accomplished one of the shortest formal total syntheses of strychnine (in ten steps and 14% overall yield or even shorter in eight steps and 10% overall yield). The evolution of a productive synthetic strategy, as well as the synthetic challenges tackled, are described here in detail, including examples of related transformations.
Leibniz-HKI-Authors
Topics
Identifier
doi: 10.1002/tcr.201500024
PMID: 26223366