Fungal RNA Biology

Our molecular and biochemical understanding of basic fungal processes lags far behind our understanding of other microbes like bacteria or viruses. We aim to level the playing field by defining novel modes of regulation for fungal RNA. These studies will provide a base for the development of future RNA-based therapeutics.


Matthew Blango
Alexander Bruch
Bhawana Israni
Abdulrahman Kelani
Xiaoqing Pan


Bruch A*, Lazarova V*, Krueger T, Schaeuble S, Kelani AA, Lehenberger P, Kniemeyer O, Panagiotou G, Blango MG (2024) Mod5 mediates a molecular trade-off between optimal gene expression and antifungal resistance. bioRxiv [Preprint]
Kelani AA, Bruch A, Rivieccio F, Visser C, Krüger T, Weaver D, Pan X, Schaeuble S, Panagiotou G, Kniemeyer O, Bromley MJ, Bowyer P, Barber AE, Brakhage AA, Blango MG (2023) Disruption of the A. fumigatus RNA interference machinery alters the conidial transcriptome. RNA 29(7), 1033-1050.