Fungal RNA Biology

Our molecular and biochemical understanding of basic fungal processes lags far behind our understanding of other microbes like bacteria or viruses. We aim to level the playing field by defining novel modes of regulation for fungal RNA. These studies will provide a base for the development of future RNA-based therapeutics.

Staff

Matthew Blango
Matthew Blango

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Alexander Bruch
Alexander Bruch

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Bhawana Israni
Bhawana Israni

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Abdulrahman Kelani
Abdulrahman Kelani

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Xiaoqing Pan
Xiaoqing Pan

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Publications

Bruch A*, Lazarova V*, Krueger T, Schaeuble S, Kelani AA, Lehenberger P, Kniemeyer O, Panagiotou G, Blango MG (2024) Mod5 mediates a molecular trade-off between optimal gene expression and antifungal resistance. bioRxiv [Preprint]
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Open Access PDF Paper
Kelani AA, Bruch A, Rivieccio F, Visser C, Krüger T, Weaver D, Pan X, Schaeuble S, Panagiotou G, Kniemeyer O, Bromley MJ, Bowyer P, Barber AE, Brakhage AA, Blango MG (2023) Disruption of the A. fumigatus RNA interference machinery alters the conidial transcriptome. RNA 29(7), 1033-1050.
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PubMed Open Access PDF Paper