(2026)
From observation to mechanistic insight: Image-based systems biology of human pathogenic fungi.
Curr Clin Microbiol Rep 13(2),
(Review)
Curriculum vitae
Main Research Areas
- Host-pathogen interaction of human pathogenic fungi
- Automated processing of microscopic images and spectroscopy data
- Spatiotemporal computer simulations of agent-based infection models
Professional Career
| since 2021 | Professor (W3) for Applied Systems Biology, Friedrich Schiller University Jena |
| since 2011 | Head of Research Group Applied Systems Biology, Leibniz-HKI |
| 2011-2021 | Professor (W2) for Applied Systems Biology, Friedrich Schiller University Jena |
| 2005-2010 | Junior Fellow in Theoretical Immunology at the Frankfurt Institute for Advanced Studies (FIAS) of the Goethe University Frankfurt |
| 2001-2005 | Research assistant in Computer Physics at the University Groningen (NL) |
| 2000 | Dr. rer. nat. in Physics at the University Groningen (NL) |
| 1995 | Diploma in Physics at the University Dortmund |
Awards · Appointments · Scientific Activities
Awards
| 2011 - 2017 | Adjunct Fellow at Frankfurt Institute for Advanced Studies (FIAS) |
Appointments and Scientific Activities
| since 2023 | Board Member and Coordinator of Task Area “Bioimage Informatics” in the DFG-funded national research data management initiative “NFDI4Bioimage” |
| since 2023 | Board Member and PI in the DFG-Research Training School RTG 2723 – “Materials-Microbes-Microenvironments” |
| since 2023 | Board Member of the Beutenberg Campus e.V. “Life Science meets Physics” |
| since 2023 | Editor: PLOS Complex Systems |
| since 2023 | Editor: Biological Imaging |
| since 2022 | Coordinator of Basic Technology 3 in the BMBF-funded “Leibniz Center for Photonics in Infection Research” |
| since 2022 | Coordinator of the BMBF-funded "Multi-Model-Simulator Project” in the funding line “Computational Life Sciences” |
| since 2021 | Deputy Coordinator of the "Jena School for Microbial Communication" |
| since 2019 | Coordinator of Research Area C – Data Synopsis in the Excellence Cluster “Balance of the Microverse” |
| since 2019 | Member of the Management Board of the Microverse Imaging Center in the Excellence Cluster “Balance of the Microverse” |
| since 2019 | Speaker and PI of Leibniz ScienceCampus “InfectoOptics” |
| since 2019 | Editor: Scientific Reports |
| since 2017 | Ombudsperson at the Leibniz Institute for Natural Product Research and Infection Biology |
| since 2017 | PI and member of the DFG-Collaborative Research Center 1278 PolyTarget |
| since 2017 | Editor: Cytometry A |
| since 2015 | Member: Jena Center for Soft Matter |
| since 2015 | Member: Michael Stifel Center for Data-Driven and Simulation Science |
| since 2014 | PI and member of the DFG-Collaborative Research Center 124 FungiNet |
| since 2012 | Organizer: Biennial international symposium on “Image-based Systems Biology” (IbSB) |
| since 2011 | Organizer: Biennial international symposium on “Systems Biology of Microbial Infection” (SBMI) |
| since 2011 | Faculty member and PI in the "International Leibniz Research School for Microbial and Biomolecular Interactions" |
| since 2011 | Faculty member and PI in the "Jena School for Microbial Communication" |
Publications
(2025)
Complex-mediated evasion: modeling defense against antimicrobial peptides with application to human-pathogenic fungus Candida albicans.
NPJ Syst Biol Appl 11(1),
81.
(2025)
Mechanistic insights into the role of extracellular vesicles at the bacterial–host interface.
ACS Infect Dis 11(12),
3407-3413.
(2025)
Generation of an induced pluripotent stem cell-derived alveolar type II in vitro model to study influenza a virus infection and drug treatments.
Adv Healthc Mater ,
e05141.
(2025)
Intuitive Abläufe für die automatisierte Bildanalyse. JIPipe als quelloffene Softwarelösung für FAIRe Bildanalyse.
Online-Publikation bei Wiley Analytical Science
(2025)
Intuitive workflows for automated image analysis - JIPipe as an open-source tool for FAIR image analysis.
Microsc Anal 39(1),
45-47.
(2025)
Multiplexed, rapid phenotypic antibiotic susceptibility testing based on angle-resolved light scattering imaging of microfluidic droplets.
J Adv Res S2090-1232(25),
00751-9.
(2025)
Rapid detection of microbial antibiotic susceptibility via deep learning supported analysis of angle-resolved scattered-light images of picoliter droplet cultivations.
Sens Actuators B Chem 424,
136866.
(2025)
Convergent evolution of a fungal effector enabling phagosome membrane penetration.
bioRxiv
[Preprint]
(2025)
Evaluating the antiviral efficacy of encapsulated PKC inhibitor BIM-I against influenza A virus infection.
Adv Healthc Mater ,
e04060.
