Clinical and epidemiological research

OncoReVir
Survival of cancer-patients infected with influenza with or without superinfection, p = 0.0035 (log-rank)
Survival of cancer-patients infected with influenza with or without superinfection, p = 0.0035 (log-rank)

We have a strong focus on unraveling the clinical relevance and the outcome of infections in patients with cancer. Here, we focus on respiratory viruses and conduct registry-studies within the cooperation OncoReVir.

An example for this work is a first analysis of the epidemiology of influenza-virus infections in cancer patients (n=210) that revealed super-infections as the most relevant risk factor for mortality (Hermann et al., Eur J Clin Microbiol Infect Dis 2017).

In addition, we investigate the role of azole-resistant Aspergillus spp. in all patient populations together with the NRZMyk and we collaborate with the University Hospital Düsseldorf in the German Keratomycosis-Registry.

Staff

Maria Rüthrich

Publications

Hermann B, Lehners N, Brodhun M, Boden K, Hochhaus A, Kochanek M, Meckel K, Mayer K, Rachow T, Rieger C, Schalk E, Weber T, Schmeier-Jürchott A, Schlattmann P, Teschner D, von Lilienfeld-Toal M (2017) Influenza virus infections in patients with malignancies -- characteristics and outcome of the season 2014/15. A survey conducted by the Infectious Diseases Working Party (AGIHO) of the German Society of Haematology and Medical Oncology (DGHO). Eur J Clin Microbiol Infect Dis 36(3), 565-573.