Gianni Panagiotou

Assoc. Prof. Dr. Gianni Panagiotou

Systems Biology and Bioinformatics · Head +49 3641 532-1759 gianni.panagiotou@leibniz-hki.de

Curriculum vitae

Main Research Areas
  • Medical & Environmental Metagenomics: human, mice, marine, plants;
  • Systems Biology: -omics integration, chemical-protein & protein-protein interaction networks; 
  • Synthetic Biology: genome-scale metabolic modelling, design of probiotics, discovery of postbiotics
Professional Career
since 2020 (Honorary) Associate Professor at the Department of Medicine and State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong.
since 2017
(Honorary) Associate Professor at the Faculty of Science, School of Biological Sciences, University of Hong Kong.
since 2017 Head of Systems Biology & Bioinformatics Unit, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knoell Institute, Jena, Germany.
2013-2017 Associate Professor at the Faculty of Science, School of Biological Sciences, The University of Hong Kong.
The University of Hong Kong places 25th in 2019 QS World University Rankings
2009-2013 Associate Professor at the Department of Systems Biology, Technical University of Denmark. 
The Technical University of Denmark places 112th in 2019 QS World University Rankings
2010 Visiting Assoc. Professor at the Industrial Biotechnology lab, Department of Chemical and Biological Engineering, Chalmers University, Sweden (January – May)
2008 Visiting Assist. Professor at the Natural Products Chemistry Lab, Department of Pharmaceutical Sciences, The University of Tokyo, Japan (January – December)
2007-2009 Assistant Professor at the Department of Systems Biology, Technical University of Denmark.
2004-2007 Post-doctoral researcher at the Department of Systems Biology, Technical University of Denmark.
2000-2004 PhD in metabolic engineering obtained from the National Technical University of Athens (16 months as guest PhD at the Technical University of Denmark).
1993-1999 Diploma (BSc & MSc) in chemical engineering obtained from the National Technical University of Athens, Greece
Awards · Appointments · Scientific Activities
2019     Organizer of the Training School “Next Generation Data Analysis” offered to the 15 PhD students of the Innovative Training Network “BestTreat”, at Hans Knöll Institute, Jena, Germany, August 28-31 (15 participants).
2019 Organizer of the workshop “RNA Sequencing Processing and Data Analysis” at Hans Knoell Institute, Jena, Germany, April 10-11 (15 participants).
2019 Organizer of the 4th International Symposium on Systems Biology of Microbial Infection in Jena, Germany, September 26-27.
2018 Lecturer at NUGO: 5th Nutrition Winter School, “Breaking barriers: Gut, Brain Bugs – and Beyond”, Levi, Finland, January 21-26.
2017 Organizer of the 4th International Symposium on Systems Biology of Microbial Infection in Jena, Germany, September 21-22.
2016 Organizer of the International “Next Generation Sequencing Data Analysis” workshop at The University of Hong Kong, Hong Kong, 15th-21st of May (50 participants).
2016 Member of the Scientific Committee of the BBW2016: Frontiers in Human Microbiota Symbiotic Interactions, Organized by Fondation IPSEN and AAAS/Science and Science Translational Medicine, Hong Kong May 23-25, 2016.
2015 Organizer of the International “Next Generation Sequencing Data Analysis” workshop at The University of Hong Kong, Hong Kong, 27th-31st of May (30 participants) and 3rd-7th of June (30 participants).
2014-2016 Responsible for the development and teaching of the course #BIOL2102 “Biostatistics” (on average 250-300 students), The University of Hong Kong (details in the Teaching Portfolio).
2014-2016 Responsible for the development and teaching (50%) of the course #BIOL3307/3409 “Business Aspects of Biotechnology” (on average 30-40 students), The University of Hong Kong (details in the Teaching Portfolio).
MEMBER URC Working Group on Entrepreneurship Development under the University Research Committee, The University of Hong Kong (nominated by the Dean for representing the Faculty of Science), 2014 – 2017.
   
  Science Faculty Information Technology Committee, The University of Hong Kong (HKU), 2014 - 2017.
   
  Career Advisory Board, The University of Hong Kong (HKU), 2015 - 2017.
   
  Strategic Research Theme of Genomics (HKU), 2013 - 2017; Strategic Research Theme for Clean Energy (HKU), 2013 - 2017; Strategic Research Theme of Integrative Biology (HKU), 2014.
       
EDITORIAL WORK Editor-in-Chief: Computational and Structural Biotechnology Journal (2018 Impact Factor of 4.2, Elsevier), 2002-2019.
   
  Guest Editor for the research topic “Systems Biology of Metabolism in Infection” for Frontiers in Cellular and Infection Microbiology, 2019
    
    
PEER EVALUATION Electoral Committee: Member of the Electoral Committee, Researcher C, “Bioinformatics or Computational Biology’’, Institute of Computer Sciences of the Foundation for Research and Technology-Hellas 2013.
    
  Electoral Committee: Member of the Electoral committee for the W3 Professorship for Genomics and Bioinformatics in Horticultural Sciences, at the Faculty of Science of the University of Potsdam, 2019.
    
    
AWARDS Research Output Prize 2017 in the Faculty of Science, The University of Hong Kong, for the article “Probiotics Modulated Gut Microbiota Suppresses Hepatocellular Carcinoma Growth in Mice”.
     
MEDIA My research has been featured in articles of South China Morning Post (Asia), Spiegel, Bild, Daily Mail (Europe), LA Times (US), among many others.
     
PATENTS WO2009144245-A1 Gianni Panagiotou, Jens Nielsen, Lisbeth Olsson. 2008. “New recombinant filamentous fungal host cell having NADH kinase activity compared to identical wild type host cell, useful for production of a polypeptide of interest useful for increasing growth rate” (Novozymes has acquired the Patent Rights)
     
  EP2062967-A1 Gianni Panagiotou, Torsten B. Regueira, Jens Nielsen, Lisbeth Olsson. 2008. ´´New genetically engineered Aspergillus overexpressing phosphoketolase useful for production of recombinant polypeptide´´

 

Publications

Patumcharoenpol P, Nakphaichit M, Panagiotou G, Senavonge A, Suratannon N, Vongsangnak W (2021) MetGEMs toolbox: Metagenome-scale models as integrative toolbox for uncovering metabolic functions and routes of human gut microbiome. PLOS Comput Biol 17(1), e1008487.
Zhang J, Ni Y, Qian L, Fang Q, Zheng T, Zhang M, Gao Q, Zhang Y, Ni J, Hou X, Bao Y, Kovatcheva-Datchary P, Xu A, Li H, Panagiotou G#, Jia W (2021) Decreased abundance of Akkermansia muciniphila leads to the impairment of insulin secretion and glucose homeostasis in lean type 2 diabetes. Adv Sci (Weinh) 8(16), e2100536.
Barber AE, Riedel J, Sae-Ong T, Kang K, Brabetz W, Panagiotou G, Deising HB, Kurzai O (2020) Effects of agricultural fungicide use on Aspergillus fumigatus abundance, antifungal susceptibility, and population structure. mBio 11(6), e02213-20.
Blango MG, Pschibul A, Rivieccio F, Krüger T, Rafiq M, Jia L, Zheng T, Goldmann M, Voltersen V, Li J, Panagiotou G, Kniemeyer O, Brakhage AA (2020) Dynamic surface proteomes of allergenic fungal conidia. J Proteome Res 19(5), 2092-2104.
Cakir T, Uddin R, Panagiotou G, Durmuş S (2020) Novel approaches for systems biology of metabolism-oriented pathogen-human interactions: A mini-review Front Cell Infect Microbiol 10, 52. (Review)
Dissanayake TK, Schäuble S, Mirhakkak MH, Wu WL, Ng CK, Yip C-Y, García-López A, Wolf T, Yeung ML, Chan KH, Yuen KY, Panagiotou G, To KKW (2020) Comparative transcriptomic analysis of rhinovirus and influenza virus infection. Front Microbiol 11(1580), 1-13.
Gill H, Leung GMK, Yim R , Lee P, Pang HH, Ip HW, Leung RYY, Li J, Panagiotou G, Ma ESK, Kwong YL (2020) Myeloproliferative neoplasms treated with hydroxyurea, pegylated interferon alpha-2A orruxolitinib: Clinicohematologic responses, quality-of-life changes and safety in the real-world setting. Hematology 25(1), 247-257.
Gill H, Yim R, Pang HH, Lee P, Chan TSY, Hwang YY, Leung GMK, Ip HW, Leung RYY, Yip SF, Kho B, Lee HKK, Mak V, Chan CC, Lau JSM, Lau CK, Lin SY, Wong RSM, Li W, Ma ESK, Li J, Panagiotou G, Sim JPY, Lie AKW, Kwong YL (2020) Clofarabine, cytarabine, and mitoxantrone in refractory/relapsed acute myeloid leukemia: High response rates and effective bridge to allogeneic hematopoietic stem cell transplantation. Cancer Med 9(10), 3371-3382.
Haange SB, Jehmlich N, Krügel U, Hintschich C, Wehrmann D, Hankir M, Seyfried F, Froment J, Hübschmann T, Müller S, Wissenbach DK, Kang K, Buettner C, Panagiotou G, Noll M, Rolle-Kampczyk U, Fenske W, von Bergen M (2020) Gastric bypass surgery in a rat model alters the community structure and functional composition of the intestinal microbiota independently of weight loss. Microbiome 8(1), 13.
Heshiki Y, Vazquez-Uribe R, Li J, Ni Y, Quainoo S, Imamovic L, Li J, Sørensen M, Chow BKC, Weiss GJ, Xu A, Sommer MOA, Panagiotou G (2020) Predictable modulation of cancer treatment outcomes by the gut microbiota. Microbiome 8(1), 28.