Curriculum vitae

Professional Career
2016 -today Junior Group Leader
2014 - 2016 PostDoc (Feodor Lynen Research Fellowship)
ETH Zurich (Jörn Piel)
Research focus: Genomics of uncultured natural product producers, biosynthesis of ribosomally produced small molecules
2011 - 2014 PostDoc
FSU Jena (Dirk Hoffmeister)
Research focus: Polyketide and nonribosomal peptide biosynthesis in mushrooms.
2006 - 2011 PhD student
HKI Jena (Christian Hertweck)
Research focus: Genomics of natural product-producing bacterial endosymbionts of fungi.
2001 - 2006 Studies of Biochemistry
FSU, Jena


Ehinger F, Niehs S, Dose B, Dell M, Krabe J, Pidot SJ, Stinear TP, Scherlach K, Ross C, Lackner G, Hertweck C (2023) Analysis of Rhizonin Biosynthesis Reveals Origin of Pharmacophoric Furylalanine Moieties in Diverse Cyclopeptides. Angew Chem Int Ed Engl , e202308540.
Löhr NA, Rakhmanov M, Wurlitzer JM, Lackner G, Gressler M, Hoffmeister D (2023) Basidiomycete non-reducing polyketide synthases function independently of SAT domains. Fungal Biol Biotechnol 10(1), 17.
Ellerhorst M, Barth SA, Graça AP, Al-Jammal WK, Peña-Ortiz L, Vilotijevic I, Lackner G# (2022) S‐Adenosylmethionine (SAM)-dependent methyltransferase MftM is responsible for methylation of the redox cofactor mycofactocin. ACS Chem Biol 17(11), 3207-3217.
Hasan M, Schulze S, Berndt L, Palm G J, Braga D, Richter I, Last D, Lammers M, Lackner G# (2022) Diversification by CofC and control by CofD govern biosynthesis and evolution of coenzyme F420 and its derivative 3PG-F420. mBio 13(1), e03501-21.
Last D, Hasan M, Rothenburger L, Braga D, Lackner G# (2022) High-yield production of coenzyme F420 in Escherichia coli by fluorescence-based screening of multi-dimensional gene expression space. Metab Eng 73, 158-167.
Um S, Guo H, Thiengmag S, Benndorf R, Murphy R, Rischer M, Braga D, Poulsen M, de Beer ZW, Lackner G, Beemelmanns C (2021) Comparative genomic and metabolic analysis of Streptomyces sp. RB110 morphotypes illuminates genomic rearrangements and formation of a new 46-membered antimicrobial macrolide. ACS Chem Biol 16(8), 1482-1492.
Braga D, Hasan M, Kröber T, Last D, Lackner G (2020) Biosynthesis of the redox coenzyme F420 in Thermomicrobia involves reduction by standalone nitroreductase superfamily enzymes. Appl Environ Microbiol 86(12), e00457-20.
Lenz C, Wick J, Braga D, Garcia-Altares M, Lackner G, Hertweck C, Gressler M, Hoffmeister D (2020) Injury-triggered blueing reactions of Psilocybe "magic" mushrooms. Angew Chem Int Ed 59(4), 1450-1454.
Peña-Ortiz L, Graça AP, Guo H, Braga D, Köllner TG, Regestein L, Beemelmanns C, Lackner G (2020) Structure elucidation of the redox cofactor mycofactocin reveals oligo-glycosylation by MftF. Chem Sci 11, 5182-5190.
Peña-Ortiz L, Schlembach I, Lackner G, Regestein L (2020) Impact of oxygen supply and scale up on Mycobacterium smegmatis cultivation and mycofactocin formation. Front Bioeng Biotechnol 8(1399), 593781.