Sphingolipid inhibitors – a novel therapeutic concept

Sphingolipid inhibitors are very different in fungi. Analysis of the different fungal genome databases suggested that in nature there are more than hundred gene clusters coding for different sphingolipid inhibitors. We are investigating the sphingolipid inhibitors’ chemical variability in order to elucidate the different mode of actions of this class of compounds.

The research group SphinX is funded by the Free State of Thuringia with means of the European Social Fund.


Vito Valiante

Dr. Vito Valiante


Phone: +49 3641 532-1090 Email: vito.valiante@leibniz-hki.de

Alexander Bissell

Alexander Bissell

Phone: +49 3641 532-1296 Email: alexander.bissell@leibniz-hki.de

Ying Huang

Ying Huang

Phone: +49 3641 532-1135 Email: ying.huang@leibniz-hki.de

Julia Rautschek

Dr. Julia Rautschek

Phone: +49 3641 532-1295 Email: julia.rautschek@leibniz-hki.de