(2024)
A highly conserved tRNA modification contributes to C. albicans filamentation and virulence.
Microbiol Spectr 12(5),
e0425522.
Publications
(2024)
The hyphal-specific toxin candidalysin promotes fungal gut commensalism.
Nature 627(8004),
620-627.
(2024)
Secretion of the fungal toxin candidalysin is dependent on conserved precursor peptide sequences.
Nat Microbiol 9(3),
669-683.
(2024)
Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFκBmediated barrier protection.
PLOS Pathog 20(3),
e1012031.
(2024)
Nanobody-mediated neutralization of candidalysin prevents epithelial damage and inflammatory responses that drive vulvovaginal candidiasis pathogenesis.
mBio 15(3),
e0340923.
(2022)
From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris.
Virulence 13(1),
191-214.
(2022)
Candidalysin is the hemolytic factor of Candida albicans.
Toxins (Basel) 14(12),
874.
(2022)
Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion.
Cell Rep 38(1),
110187.
(2021)
A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis.
PLOS Pathog 17(9),
e1009884.
(2021)
Candidalysin delivery to the invasion pocket is critical for host epithelial damage induced by Candida albicans.
Cell Microbiol 23(10),
e13378.