Curriculum vitae

Main Research Areas
  • Infection biology of human pathogenic fungi (Candida albicans)
  • Immunology of fungal infections
  • Host-pathogen interactions
  • Fungal adaptation to the host
Professional Career
Since
05/2020
Junior Research Group Leader, Leibniz Institute of Natural Product Research and Infection Biology - Hans Knoell Institute, Adaptive Pathogenicity Strategies
05/2018-
05/2020
Alexander von Humboldt Foundation Postdoctoral Fellowship, Leibniz Institute of Natural Product Research and Infection Biology - Hans Knoell Institute, Dept. Microbial Pathogenicity Mechanisms
03/2018-04/2018 Language Course German, Dresden, Germany
08/2015-03/2018 Postdoctoral researcher, Radboud University Medical Center, Department of Internal medicine, Nijmegen Institute for Infectious Diseases. Project: The development of novel immunomodulatory strategies for disseminated fungal infections
10/2010-05/2015 Phd, Radboud University Nijmegen Medical Center, department of internal medicine, Nijmegen, The Netherlands. Project: Pattern recognition and cytokine signalling pathways in the host defence against Aspergillus fumigatus
02/2008-08/2010 M.Sc. Medical Biology, Radboud University, Nijmegen, The Netherlands
07/2003-07/2007 B.Sc. Biology and Medical Laboratory Research, Saxion University of Applied Sciences, Enschede, The Netherlands
Awards · Appointments · Scientific Activities
2021 Research award of the German speaking society for Mycology (DMykG)
2021 Science Award Life Sciences and Physics 2021 Beutenberg Campus e.V. Jena
Since 2021 Member and PI of the DFG SFB/TR 124 programme "Pathogenic fungi and their human host: Networks of interaction – FungiNet'"
Since 2020 DFG Emmy Noether grant
2020 Journal of Fungi Travel Award
2020 Co-Organizer of the FEBS advanced practical course “State-of-the-art infection models for human pathogenic fungi” in Jena, Germany
2019 PLoS Pathogens Postdoctoral Poster Award, Advanced lecture course on Human Fungal Pathogens
2019 ESCMID Research Grant 2019
2019 Co-organizer of the winter school of the FunHoMic Marie Curie International Training Network
2018-2021 Two publication awards of the Deutschsprachigen Mykologischen Gesellschaft (DMykG; as co-author)
2018 Humboldt Research Fellowship for Postdoctoral Researchers
2018 Golden pipette award by the Laboratory for Experimental Internal Medicine Radboud University Nijmegen Medical center
2016 3rd prize for best thesis by the Radboud institute for molecular life sciences (RIMLS)
2015 Van Beckum thesis Award for best PhD thesis in the field of immunology by the Dutch society for Immunology (NVVI)
2015 Youth development Prize by the German speaking society for Mycology (DMykG)
Since 2014 Ad hoc reviewer for 19 journals eLife, PLoS Pathogens, mBio, Journal of Infectious Diseases, Frontiers Immunology, Cellular Microbiology, FEMS microbiology letters, Microbial Pathogenesis, Virulence, and others
2013 ALLFUN Investigators Award

Publications

Delsing CE, Gresnigt MS, Leentjens J, Preijers F, Frager FA, Kox M, Monneret G, Venet F, Bleeker-Rovers CP, van de Veerdonk FL, Pickkers P, Pachot A, Kullberg BJ, Netea MG (2014) Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series. BMC Infect Dis 14, 166.
Gresnigt MS, Bozza S, Becker KL, Joosten LA, Abdollahi-Roodsaz S, van der Berg WB, Dinarello CA, Netea MG, Fontaine T, De Luca A, Moretti S, Romani L, Latge JP, van de Veerdonk FL (2014) A polysaccharide virulence factor from Aspergillus fumigatus elicits anti-inflammatory effects through induction of Interleukin-1 receptor antagonist. PLOS Pathog 10(3), e1003936.
Gresnigt MS, van de Veerdonk FL (2014) The role of interleukin-1 family members in the host defence against Aspergillus fumigatus. Mycopathologia 178(5-6), 395-401.
van de Veerdonk FL, Gresnigt MS, Oosting M, van der Meer JW, Joosten LA, Netea MG, Dinarello CA (2014) Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37. Front Microbiol 5, 762.
van Poppel PC, Gresnigt MS, Smits P, Netea MG, Tack CJ (2014) The dipeptidyl peptidase-4 inhibitor vildagliptin does not affect ex vivo cytokine response and lymphocyte function in patients with type 2 diabetes mellitus. Diabetes Res Clin Pract 103(3), 395-401.
Gresnigt MS, Becker KL, Smeekens SP, Jacobs CW, Joosten LA, van der Meer JW, Netea MG, van de Veerdonk FL (2013) Aspergillus fumigatus-induced IL-22 is not restricted to a specific Th cell subset and is dependent on complement receptor 3. J Immunol 190(11), 5629-5639.
Gresnigt MS, Rösler B, Jacobs CW, Becker KL, Joosten LA, van der Meer JW, Netea MG, Dinarello CA, van de Veerdonk FL (2013) The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses. Eur J Immunol 43(2), 416-426.
Gresnigt MS, van de Veerdonk FL (2013) Biology of IL-36 cytokines and their role in disease. Semin Immunol 25(6), 458-465.
Kyrmizi I, Gresnigt MS, Akoumianaki T, Samonis G, Sidiropoulos P, Boumpas D, Netea MG, van de Veerdonk FL, Kontoyiannis DP, Chamilos G (2013) Corticosteroids block autophagy protein recruitment in Aspergillus fumigatus phagosomes via targeting dectin-1/Syk kinase signaling. J Immunol 191(3), 1287-1299.
Smeekens SP, Ng A, Kumar V, Johnson MD, Plantinga TS, van Diemen C, Arts P, Verwiel ET, Gresnigt MS, Fransen K, van Sommeren S, Oosting M, Cheng SC, Joosten LA, Hoischen A, Kullberg BJ, Scott WK, Perfect JR, van der Meer JW, Wijmenga C, Netea MG, Xavier RJ (2013) Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans. Nat Commun 4, 1342.

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