Topics

Publications

Jia LJ#, González K*, Orasch T*, Schmidt F*, Brakhage AA# (2024) Manipulation of host phagocytosis by fungal pathogens and therapeutic opportunities. Nat Microbiol 9(9), 2216-2231. (Review)
Goldmann M*, Schmidt F*, Cseresnyés Z, Orasch T, Jahreis S, Hartung S, Figge MT, von Lilienfeld-Toal M, Heinekamp T, Brakhage AA# (2023) The lipid raft-associated protein stomatin is required for accumulation of dectin-1 in the phagosomal membrane and for full activity of macrophages against Aspergillus fumigatus. mSphere 8(1), e00523-22.
González K*, Gangapurwala G*, Alex J*, Vollrath A, Cseresnyés Z, Weber C, Czaplewska JA, Hoeppener S, Svensson CM, Orasch T, Heinekamp T, Guerrero-Sánchez C, Figge MT, Schubert US, Brakhage AA (2023) Targeting of phagolysosomes containing conidia of the human pathogenic fungus Aspergillus fumigatus with polymeric particles. Appl Microbiol Biotechnol 107(2-3), 819-834.
Orasch T*, Gangapurwala G*, Vollrath A, González K, Alex J, De San Luis A, Weber C, Hoeppener S, Cseresnyés Z, Figge MT, Guerrero-Sanchez C, Schubert US#, Brakhage AA# (2023) Polymer-based particles against pathogenic fungi: A non-uptake delivery of compounds. Biomater Adv 146, 213300.
Aguiar M, Orasch T, Shadkchan Y, Caballero P, Pfister J, Sastré-Velásquez LE, Gsaller F, Decristoforo C, Osherov N, Haas H (2022) Uptake of the Siderophore Triacetylfusarinine C, but Not Fusarinine C, Is Crucial for Virulence of Aspergillus fumigatus. mBio 13(5), e0219222.
Aguiar M, Orasch T, Misslinger M, Dietl AM, Gsaller F, Haas H (2021) The Siderophore Transporters Sit1 and Sit2 Are Essential for Utilization of Ferrichrome-, Ferrioxamine- and Coprogen-Type Siderophores in Aspergillus fumigatus. J Fungi (Basel) 7(9),
Alex J, Gonzalez K, Kindel T, Bellstedt P, Weber C, Heinekamp T, Orasch T, Guerrero-Sanchez C, Schubert US, Brakhage AA (2020) Caspofungin functionalized polymethacrylates with antifungal properties. Biomacromolecules 21(6), 2104-2115.
Pahlow S, Orasch T, Žukovskaja O, Bocklitz T, Haas H, Weber K (2020) Rapid detection of the aspergillosis biomarker triacetylfusarinine C using interference-enhanced Raman spectroscopy. Anal Bioanal Chem 412(24), 6351-6360.
Pfister J, Summer D, Petrik M, Khoylou M, Lichius A, Kaeopookum P, Kochinke L, Orasch T, Haas H, Decristoforo C (2020) Hybrid Imaging of Aspergillus fumigatus Pulmonary Infection with Fluorescent, 68Ga-Labelled Siderophores. Biomolecules 10(2),
Bauer I, Misslinger M, Shadkchan Y, Dietl AM, Petzer V, Orasch T, Abt B, Graessle S, Osherov N, Haas H (2019) The Lysine Deacetylase RpdA Is Essential for Virulence in Aspergillus fumigatus. Front Microbiol 10, 2773.