Curriculum vitae

Main Research Areas
  • Disease Tolerance to Infection
  • Innate Immunity
  • Heme Metabolism
  • Metabolic Adaptation
  • Sepsis
  • Staphylococcus aureus Bacteremia
Professional Career
since 2021 W3 Professor for "Translational Infection Research", FSU Jena
since 2021 Member of the Ethics Committee, FSU Jena
2021 Call W2 Professorship "Inflammation and Haematopoiesis", TU Dresden, declined
2019 Senior Physician, Institute for Infectious Medicine and Hospital Hygiene
2019 Call W3 Professorship "Clinical Infectious Disease", Tübingen, declined
2019 Call W2 professorship "Clinical Infectiology and Immunology", UKE Hamburg, declined
seit 2019 Subgroup Coordinator, Cluster of Excellence "Balance of the Microverse", FSU Jena
2018 Subspecialisation in Clinical Infectious Disease
2018 Member of the Board IFB Center for Sepsis Control and Care, FSU Jena
2018 Member Cluster of Excellence "Balance of the Microverse”, FSU Jena
2018 Examiner 3rd State Examination in Human Medicine
2017 Habilitation and Venia legendi Internal Medicine, FSU Jena
2015 Training in Clinical Infectiology with Prof. M.W. Pletz, JUH
2012-2015 Postdoctoral Fellow, Instituto Gulbenkian de Ciência (IGC), Portugal
2012 Specialist Examination in Internal Medicine
2007-2012 Specialist Training in Internal Medicine with Prof. J.Mössner, Leipzig University Hospital and Prof. G.Hindricks, Heart Center Leipzig
2008 Medical Dissertation “On Paraenzymatic Functions of Heme Oxygenease-1” (summa cum laude), University of Leipzig, Germany
2007 Visiting Researcher, MRC Fajara, The Gambia, West-Afrika
2006 Approbation/Physician's license
2005 Clinical Elective, Medical Research Council, Fajara, The Gambia
2002-2003 Visiting Researcher, Dept. of Pediatrics, Stanford University, USA
1999-2006 Studies of Medicine, University of Leipzig, Germany; Practical Year: Children´s Hospital of Philadelphia, USA and St. Georg Hospital, Leipzig, Germany
Awards · Appointments · Scientific Activities
2018 Winner Science Slam, KIT 2018
2018 Best Oral Presentation Award, 10th Meeting of HO, Seoul
2017 Hugo-Schottmüller Award of the German Sepsis Society
2017 Best Abstract Award, International Sepsis Forum
2012-2014 DFG Fellowship for Research Abroad
2010 Formula 1 Research Fellowship, University of Leipzig
2008 Doberentz Prize of the University of Leipzig for Outstanding Dissertations

Publications

Colaço HG, Barros A, Neves-Costa A, Seixas E, Pedroso D, Velho T, Willmann KL, Faisca P, Grabmann G, Yi HS, Shong M, Benes V, Weis S, Köcher T, Moita LF (2021) Tetracycline Antibiotics Induce Host-Dependent Disease Tolerance to Infection. Immunity 54(1), 53-67.e7.
Divangahi M, Aaby P, Khader SA, Barreiro LB, Bekkering S, Chavakis T, van Crevel R, Curtis N, DiNardo AR, Dominguez-Andres J, Duivenvoorden R, Fanucchi S, Fayad Z, Fuchs E, Hamon M, Jeffrey KL, Khan N, Joosten LAB, Kaufmann E, Latz E, Matarese G, van der Meer JWM, Mhlanga M, Moorlag SJCFM, Mulder WJM, Naik S, Novakovic B, O'Neill L, Ochando J, Ozato K, Riksen NP, Sauerwein R, Sherwood ER, Schlitzer A, Schultze JL, Sieweke MH, Benn CS, Stunnenberg H, Sun J, van de Veerdonk FL, Weis S, Williams DL, Xavier R, Netea MG (2021) Trained immunity, tolerance, priming and differentiation: distinct immunological processes. Nat Immunol 22(1), 2-6.
Jentho E, Ruiz-Moreno C, Novakovic B, Kourtzelis I, Megchelenbrink WL, Martins R, Chavakis T, Soares MP, Kalafati L, Guerra J, Roestel F, Bohm P, Godmann M, Grinenko T, Eugster A, Beretta M, Joosten LAB, Netea MG, Bauer M, Stunnenberg HG, Weis S (2021) Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme. Proc Natl Acad Sci U S A 118(42),
Jentho E, Weis S (2021) DAMPs and Innate Immune Training Front Immunol [Accepted]
Mourits VP, van Puffelen JH, Novakovic B, Bruno M, Ferreira AV, Arts RJ, Groh L, Crișan TO, Zwaag J, Jentho E, Kox M, Pickkers P, van de Veerdonk FL, Weis S, Oosterwijk E, Vermeulen SH, Netea MG, Joosten LA (2021) Lysine methyltransferase G9a is an important modulator of trained immunity. Clin Transl Immunology 10(2), e1253.
Osuchowski MF, Winkler MS, Skirecki T, Cajander S, Shankar-Hari M, Lachmann G, Monneret G, Venet F, Bauer M, Brunkhorst FM, Weis S, Garcia-Salido A, Kox M, Cavaillon JM, Uhle F, Weigand MA, Flohé SB, Wiersinga WJ, Almansa R, de la Fuente A, Martin-Loeches I, Meisel C, Spinetti T, Schefold JC, Cilloniz C, Torres A, Giamarellos-Bourboulis EJ, Ferrer R, Girardis M, Cossarizza A, Netea MG, van der Poll T, Bermejo-Martín JF, Rubio I (2021) The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity. Lancet Respir Med 9(6), 622-642. (Review)
Scholz J, Wetzker W, Licht A, Heintzmann R, Scherag A, Weis S, Pletz M, Betsch C, Bauer M, Dickmann P (2021) The role of risk communication in public health interventions. An analysis of risk communication for a community quarantine in Germany to curb the SARS-CoV-2 pandemic. PLoS One 16(8), e0256113.
Vandewalle J, Timmermans S, Paakinaho V, Vancraeynest L, Dewyse L, Vanderhaeghen T, Wallaeys C, Van Wyngene L, Van Looveren K, Nuyttens L, Eggermont M, Dewaele S, Velho TR, Moita LF, Weis S, Sponholz C, van Grunsven LA, Dewerchin M, Carmeliet P, De Bosscher K, Van de Voorde J, Palvimo JJ, Libert C (2021) Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis. Cell Metab 33(9), 1763-11776.e5.
Weis S, Scherag A, Baier M, Kiehntopf M, Kamradt T, Kolanos S, Ankert J, Glöckner S, Makarewicz O, Hagel S, Bahrs C, Kimmig A, Proquitté H, Guerra J, Rimek D, Löffler B, Pletz MW (2021) Antibody response using six different serological assays in a completely PCR-tested community after a coronavirus disease 2019 outbreak-the CoNAN study. Clin Microbiol Infect 27(3), 470.e1-470.e9.
Winkler MS, Skirecki T, Brunkhorst FM, Cajander S, Cavaillon JM, Ferrer R, Flohé SB, García-Salido A, Giamarellos-Bourboulis EJ, Girardis M, Kox M, Lachmann G, Martin-Loeches I, Netea MG, Spinetti T, Schefold JC, Torres A, Uhle F, Venet F, Weis S, Scherag A, Rubio I, Osuchowski MF (2021) Bridging animal and clinical research during SARS-CoV-2 pandemic: A new-old challenge. EBioMedicine 66, 103291. (Review)