Dr. Florian Kloß

Alumni

Publications

Barth SA, Preussger D, Pietschmann J, Feßler AT, Heller M, Herbst W, Schnee C, Schwarz S, Kloss F, Berens C, Menge C (2024) In vitro antibacterial activity of microbial natural products against bacterial pathogens of veterinary and zoonotic relevance. Antibiotics (Basel) 13(2), 135.
Keiff F, Bernal FA, Joch M, Jacques Dit Lapierre TJW, Li Y, Liebing P, Dahse HM, Vilotijevic I, Kloss F (2024) Modulation of the Meisenheimer complex metabolism of nitro-benzothiazinones by targeted C-6 substitution. Commun Chem 7(1), 153.
Richter I, Hasan M, Kramer JW, Wein P, Krabbe J, Woitas KP, Stinear TP, Pidot SJ, Kloss F, Hertweck C, Lackner G (2024) Deazaflavin metabolite produced by endosymbiotic bacteria controls fungal host reproduction. ISME J 18(1), wrae074.
Torres-Gómez H, Keiff F, Hortschansky P, Bernal F, Kerndl V, Meyer F, Messerschmidt N, Dal Molin M, Krüger T, Rybniker J, Brakhage AA, Kloss F (2024) Replacement of the essential nitro group by electrophilic warheads towards nitro-free antimycobacterial benzothiazinones. Eur J Med Chem 279, 116849.
Chalo DM, Franke K, Nchiozem-Ngnitedem VA, Kakudidi E, Origa-Oryem H, Namukobe J, Kloss F, Yenesew A, Wessjohann LA (2023) Prenylated isoflavanones with antimicrobial potential from the root bark of Dalbergia melanoxylon. Metabolites 13(6), 678.
Eckhardt E, Li Y, Mamerow S, Schinköthe J, Sehl-Ewert J, Dreisbach J, Corleis B, Dorhoi A, Teifke J, Menge C, Kloss F, Bastian M (2023) Pharmacokinetics and efficacy of the Benzothiazinone BTZ-043 against Tuberculous Mycobacteria inside granulomas in the Guinea pig model. Antimicrob Agents Chemother 67(4), e0143822.
Joch M, Wojtas KP, Torres-Gómez H, Li Y, Meyer F, Straßburger M, Kerndl V, Dahse HM, Hertweck C, Hoffmann H, Görls H, Walter K, Hölscher C, Kloss F (2023) Whole cell hydride Meisenheimer complex biotransformation guided optimization of antimycobacterial benzothiazinones. Eur J Med Chem 264, 116023.
Keiff F, Jacques dit Lapierrev TJW, Bernal F, Kloss F (2023) Design and synthesis of benzofuran- and naphthalene-fused thiazinones as antimycobacterial agents. Arch Pharm (Weinheim) 356(11), e2300356.
Alt S, Haggstrom D, Kessmann H, Kloss F, Schneider CE, Jäger T, Schwede T, Brakhage A, Dehio C (2022) INCATE: a partnership to boost the antibiotic pipeline. Nat Rev Drug Discov 21(9), 621-622. (Review)
Bernal FA, Hammann P, Kloss F (2022) Natural products in antibiotic development: is the success story over? Curr Opin Biotechnol 78, 102783. (Review)