Curriculum vitae

Main Research Areas
  • Immune escape of human pathogenic micro-organisms
  • Infection-associated function of the complement system
  • Genetic susceptibility for infections
Professional Career
Since 2000 Professor for infection biology, Friedrich-Schiller-University Jena (FSU Jena) 
Since 2000 Head of the department infection biology, Leibniz-Institute for Natural Product Research and Infection Biology – Hans-Knöll-Institute Jena
1999 Nontenured professor, University Hamburg
1993 Habilitation in immunology and molecular biology, University Hamburg
1989-2000 Group head at the Bernhard-Nocht-Institute for tropical medicine Hamburg
1989 Visiting associate, Laboratory of Immunoregulation, National Institutes of Health, Bethesda, Maryland, USA
1985-1988 Postdoc, Laboratory of Immunoregulation, National Institutes of Health, Bethesda, Maryland, USA, funded by the German Academic Exchange Service (DAAD)
1984 PhD as Dr. rer. nat., University Bremen
1980-1985 Research assistant, University Bremen
1980 Diploma in biology, University Bremen



Awards · Appointments · Scientific Activities
Since 2009  Member at the editorial board of molecular immunology, frontiers in innate immunity
2009 Excellence award from the Deutsche Gesellschaft für Hygiene und Mikrobiologie
Since 2008 Representative of the graduate school International Leibniz Research School for Microbial and Biomolecular Interactions (ILRS)
2008 EFIS lecture award of the European Federation of Immunological Societies
Since 2007 Principal investigator of the excellence graduate school Jena School for Microbial Communication (JSMC)
2007 Heinz Spitzbart award of the European Society for Infectious Diseases in Obstetrics and Gynaecology (ESIDOG)
Since 2006 Principal investigator of the graduate school International Leibniz Research School for Microbial and Biomolecular Interactions (ILRS)
2007-2011 President of the European Complement Network
2005 – 2012 Board member of the European Complement Network
2004 Thuringian research award
Since 2002 Deputy Director of the Leibniz-Institute for Natural Product Research and Infection Biology – Hans-Knöll-Institute Jena
Since 2000 Project leader for infection biology, L2
1999-2001 Member at the editorial board of experimental and clinical immunology, thrombosis and haemostasis, section editor molecular immunology
Member of the European Working Party on the Genetics of Complement mediated Kidney Diseases, Deutsche Gesellschaft für Hygiene und Mikrobiologie (DGHM), Deutsche Gesellschaft für Immunologie, Gesellschaft für Genetik, Gesellschaft für Nephrologie

Publications

Zipfel PF, Lauer N (2013) Defective complement action and control defines disease pathology for retinal and renal disorders and provides a basis for new therapeutic approaches. Adv Exp Med Biol 735, 173-187.
Zipfel PF, Skerka C, Hallström T, Wolf G (2013) 14th European Meeting on Complement in Human Disease, Jena, Germany, August 17-21, 2013. Mol Immunol 56(3), 151-151.
Barthel D, Schindler S, Zipfel PF (2012) Plasminogen is a complement inhibitor. J Biol Chem 287(22), 18831-18842.
Barthel D, Singh B, Riesbeck K, Zipfel PF (2012) Haemophilus influenzae uses the surface protein E to acquire human plasminogen and to evade innate immunity. J Immunol 188(1), 379-385.
Citiulo F, Jacobsen ID, Miramón P, Schild L, Brunke S, Zipfel PF, Brock M, Hube B, Wilson D (2012) Candida albicans scavenges host zinc via Pra1 during endothelial invasion. PLOS Pathog 8(6), e1002777.
Foltyn Zadura A, Zipfel PF, Bokarewa MI, Sturfelt G, Jönsen A, Nilsson SC, Hillarp A, Saxne T, Trouw LA, Blom AM (2012) Factor H autoantibodies and deletion of Complement Factor H-Related protein-1 in rheumatic diseases in comparison to atypical hemolytic uremic syndrome. Arthritis Res Ther 14(4), R185.
Hallström T, Mörgelin M, Barthel D, Raguse M, Kunert A, Hoffmann R, Skerka C, Zipfel PF (2012) Dihydrolipoamide dehydrogenase of Pseudomonas aeruginosa is a surface-exposed immune evasion protein that binds three members of the factor H family and plasminogen. J Immunol 189(10), 4939-4950.
Hammerschmidt C, Hallström T, Skerka C, Wallich R, Stevenson B, Zipfel PF, Kraiczy P (2012) Contribution of the infection-associated complement regulator-acquiring surface protein 4 (ErpC) to complement resistance of Borrelia burgdorferi. Clin Dev Immunol 2012, 349657.
Noone D, Al-Matrafi J, Tinckam K, Zipfel PF, Herzenberg AM, Thorner PS, Pluthero FG, Kahr WH, Filler G, Hebert D, Harvey E, Licht C (2012) Antibody mediated rejection associated with complement factor h-related protein 3/1 deficiency successfully treated with eculizumab. Am J Transplant 12(9), 2546-2553.
Schindler MK, Schütz MS, Mühlenkamp MC, Rooijakkers SH, Hallström T, Zipfel PF, Autenrieth IB (2012) Yersinia enterocolitica YadA mediates complement evasion by recruitment and inactivation of C3 products. J Immunol 189(10), 4900-4908.