Curriculum vitae

Main Research Areas
  • Immune escape of human pathogenic micro-organisms
  • Infection-associated function of the complement system
  • Genetic susceptibility for infections
Professional Career
Since 2000 Professor for infection biology, Friedrich-Schiller-University Jena (FSU Jena) 
Since 2000 Head of the department infection biology, Leibniz-Institute for Natural Product Research and Infection Biology – Hans-Knöll-Institute Jena
1999 Nontenured professor, University Hamburg
1993 Habilitation in immunology and molecular biology, University Hamburg
1989-2000 Group head at the Bernhard-Nocht-Institute for tropical medicine Hamburg
1989 Visiting associate, Laboratory of Immunoregulation, National Institutes of Health, Bethesda, Maryland, USA
1985-1988 Postdoc, Laboratory of Immunoregulation, National Institutes of Health, Bethesda, Maryland, USA, funded by the German Academic Exchange Service (DAAD)
1984 PhD as Dr. rer. nat., University Bremen
1980-1985 Research assistant, University Bremen
1980 Diploma in biology, University Bremen



Awards · Appointments · Scientific Activities
Since 2009  Member at the editorial board of molecular immunology, frontiers in innate immunity
2009 Excellence award from the Deutsche Gesellschaft für Hygiene und Mikrobiologie
Since 2008 Representative of the graduate school International Leibniz Research School for Microbial and Biomolecular Interactions (ILRS)
2008 EFIS lecture award of the European Federation of Immunological Societies
Since 2007 Principal investigator of the excellence graduate school Jena School for Microbial Communication (JSMC)
2007 Heinz Spitzbart award of the European Society for Infectious Diseases in Obstetrics and Gynaecology (ESIDOG)
Since 2006 Principal investigator of the graduate school International Leibniz Research School for Microbial and Biomolecular Interactions (ILRS)
2007-2011 President of the European Complement Network
2005 – 2012 Board member of the European Complement Network
2004 Thuringian research award
Since 2002 Deputy Director of the Leibniz-Institute for Natural Product Research and Infection Biology – Hans-Knöll-Institute Jena
Since 2000 Project leader for infection biology, L2
1999-2001 Member at the editorial board of experimental and clinical immunology, thrombosis and haemostasis, section editor molecular immunology
Member of the European Working Party on the Genetics of Complement mediated Kidney Diseases, Deutsche Gesellschaft für Hygiene und Mikrobiologie (DGHM), Deutsche Gesellschaft für Immunologie, Gesellschaft für Genetik, Gesellschaft für Nephrologie

Publications

Pollmächer J, Timme S, Schuster S, Brakhage AA, Zipfel PF, Figge MT (2016) Deciphering the counterplay of Aspergillus fumigatus infection and host inflammation by evolutionary games on graphs. Sci Rep 6, 27807.
Rosa TF, Flammersfeld A, Ngwa CJ, Kiesow M, Fischer R, Zipfel PF, Skerka C, Pradel G (2016) The Plasmodium falciparum blood stages acquire factor H family proteins to evade destruction by human complement. Cell Microbiol 18(4), 573-590.
Schäfer N, Grosche A, Reinders J, Hauck SM, Pouw RB, Kuijpers TW, Wouters D, Ehrenstein B, Enzmann V, Zipfel PF, Skerka C, Pauly D (2016) Complement Regulator FHR-3 Is Elevated either Locally or Systemically in a Selection of Autoimmune Diseases. Front Immunol 7, 542.
Taudien S, Lausser L, Giamarellos-Bourboulis EJ, Sponholz C, Schöneweck F, Felder M, Schirra LR, Schmid F, Gogos C, Groth S, Petersen BS, Franke A, Lieb W, Huse K, Zipfel PF, Kurzai O, Moepps B, Gierschik P, Bauer M, Scherag A, Kestler HA, Platzer M (2016) Genetic Factors of the Disease Course After Sepsis: Rare Deleterious Variants Are Predictive. EBioMedicine 12, 227-238.
Weiss R, Rosendahl A, Czesla D, Meyer-Schwesinger C, Stahl R, Ehmke, H, Kurts C, Zipfel PF, Köhl J, Wenzel U (2016) The complement receptor C5aR1 contributes to renal damage but protects the heart in angiotensin II-induced hypertension Am J Ren Physiol 310(11), F1356-F1365.
Bradley DT, Bourke TW, Fairley DJ, Borrow R, Shields MD, Zipfel PF, Hughes AE (2015) Susceptibility to invasive meningococcal disease: polymorphism of complement system genes and Neisseria meningitidis factor H binding protein. PLOS One 10(3), e0120757.
Duehring S, Germerodt S, Skerka C, Zipfel PF, Dandekar T, Schuster S (2015) Host-pathogen interactions between the human innate immune system and Candida albicans - Understanding and modeling defense and evasion strategies Front Microbiol 6, 625.
Garrone A, Archipowa N, Zipfel PF, Hermann G, Dietzek B (2015) Plant Protochlorophyllide Oxidoreductases A and B - Catalytic Efficiency and Initial Reaction Steps. J Biol Chem 290(47), 28530-28539.
Genewsky A, Jost I, Busch C, Huber C, Stindl J, Skerka C, Zipfel PF, Rohrer B, Strauß O (2015) Activation of endogenously expressed ion channels by active complement in the retinal pigment epithelium. Pflugers Arch 467(10), 2179-2191.
Hallström T, Uhde M, Singh B, Skerka C, Riesbeck K, Zipfel PF (2015) Pseudomonas aeruginosa Uses Dihydrolipoamide Dehydrogenase (Lpd) to Bind to the Human Terminal Pathway Regulators Vitronectin and Clusterin to Inhibit Terminal Pathway Complement Attack. PLOS One 10(9), e0137630.