Publications

Ishida K, Shabuer G, Schieferdecker S, Pidot SJ, Stinear TP, Knuepfer U, Cyrulies M, Hertweck C (2020) Oak-associated negativicute equipped with ancestral aromatic polyketide synthase produces antimycobacterial dendrubins. Chem Eur J 26(58), 13147-13151.
Neuwirth T, Letzel AC, Tank C, Ishida K, Cyrulies M, Schmölz L, Lorkowski S, Hertweck C (2020) Induced production, synthesis and immunomodulatory action of clostrisulfone, a diarylsulfone from Clostridium acetobutylicum. Chemistry 26(68), 15855-15858.
Niehs SP, Kumpfmüller J, Dose B, Little RF, Ishida K, Florez LV, Kaltenpoth M, Hertweck C (2020) Insect-associated bacteria assemble the antifungal butenolide gladiofungin by non-canonical polyketide chain termination. Angew Chem Int Ed 59(51), 23122-23126.
Trottmann F, Ishida K, Franke J, Stanišić A, Ishida-Ito M, Kries H, Pohnert G, Hertweck C (2020) Sulfonium acids loaded onto an unusual thiotemplate assembly line construct the cyclopropanol warhead of a Burkholderia virulence factor. Angew Chem Int Ed 59(32), 13511-13515.
Bratovanov EV, Ishida K, Heinze B, Pidot SJ, Stinear TP, Hegemann JD, Marahiel MA, Hertweck C (2019) Genome mining and heterologous expression reveal two distinct families of lasso peptides highly conserved in endofungal bacteria. ACS Chem Biol 15(5), 1169-1176.
Herisse M, Ishida K, Porter JL, Howden B, Hertweck C, Stinear TP, Pidot SJ (2019) Identification and mobilization of a cryptic antibiotic biosynthesis gene locus from a human-pathogenic nocardia isolate. ACS Chem Biol 15(5), 1161-1168.
Hermenau R, Mehl JL, Ishida K, Dose B, Ishida-Ito M, Pidot SJ, Stinear TP, Hertweck C (2019) Genomics-driven discovery of NO-donating diazeniumdiolate siderophores in diverse plant-associated bacteria. Angew Chem Int Ed 58(37), 13024-13029.
Pancrace C, Ishida K, Briand E, Gatte Pichi D, Weiz AR, Guljamow A, Scalvenzi T, Sassoon N, Hertweck C, Dittmann E, Gugger M (2019) Unique biosynthetic pathway in bloom-forming cyanobacterial genus Microcystis jointly assembles cytotoxic aeruginoguanidines and microguanidines. ACS Chem Biol 14(1), 67-75.
Peng H, Ishida K, Hertweck C (2019) Loss of single domain function in modular assembly line alters size and shape of complex polyketide. Angew Chem Int Ed 58(50), 18252-18256.
Peng H, Ishida K, Sugimoto Y, Jenke-Kodama H, Hertweck C (2019) Emulating evolutionary processes to morph aureothin-type modular polyketide synthases and associated oxygenases. Nat Commun 10(1), 3918.