(2015)
Freedom and constraint in engineered noncolinear polyketide assembly lines
Chem Biol 22(2),
229-240.
Topics
Publications
(2014)
Total synthesis of the antitumor natural product polycarcin V and evaluation of its DNA binding profile.
Org Lett 16(11),
2962-2965.
(2014)
Evolution of siderophore pathways in human pathogenic bacteria.
J Am Chem Soc 136(15),
5599-5602.
(2014)
Functional analysis of environmental DNA-derived microviridins provides new insights into the diversity of the tricyclic peptide family.
Appl Environ Microbiol 80(4),
1380-1387.
(2014)
Rational design of modular polyketide synthases: morphing the aureothin pathway into a luteoreticulin assembly line.
Angew Chem Int Ed Engl 53(6),
1560-1564.
(2014)
Harnessing the evolvability of tricyclic microviridins to dissect protease-inhibitor interactions.
Angew Chem Int Ed Engl 53(14),
3735-3738.
(2013)
Nitro versus hydroxamate in siderophores of pathogenic bacteria: effect of missing hydroxylamine protection in malleobactin biosynthesis.
Angew Chem Int Ed Engl 52(32),
8271-8275.
(2012)
Antiterminator-mediated unveiling of cryptic polythioamides in an anaerobic bacterium.
Angew Chem Int Ed Engl 51(10),
2425-2428.
(2012)
Assembly and absolute configuration of short-lived polyketides from Burkholderia thailandensis.
Angew Chem Int Ed Engl 51(22),
5470-5474.
(2012)
Pyran formation by an atypical CYP-mediated four-electron oxygenation-cyclization cascade in an engineered aureothin pathway.
Chembiochem 13(15),
2196-2199.