Curriculum vitae

Main Research Areas
  • Biochemical and genetic basis of fungal natural product biosyntheses
  • Natural products of basidiomycetes and Ralstonia solanacearum
  • Microbial nonribosomal peptide synthetases
Professional Career
2014- Full Professor for Pharmaceutical Microbiology, FSU Jena and HKI Jena
2009-2014 Associate Professor for Pharmaceutical Biology, FSU Jena and head of the associated department Pharmaceutical Biology at the HKI Jena
2007-2009 Assistant professor (tenure track) University of Minnesota, Saint Paul, MN, USA
2008 Habilitation in Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University Freiburg
2004-2007 Research assistant, Institute for Pharmacy, Albert-Ludwigs-University, Freiburg
2002-2004 Postdoc, University of Wisconsin, Madison, WI, USA (DFG-fellowship)
2002 Dr. rer. nat., Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University, Freiburg
1998 Diploma in biology at the Eberhard-Karls-University, Tübingen
Awards · Appointments · Scientific Activities
Since 2016 Dean for Study Affairs in the Faculty of Biology and Pharmacy, FSU Jena
2013-2016 Scientific advisory board, Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM).
Since 2011 Member of the editorial board of various journals

Publications

Fricke J, Sherwood AM, Halberstadt AL, Kargbo RB, Hoffmeister D (2021) Chemoenzymatic synthesis of 5-methylpsilocybin: A tryptamine with potential psychedelic activity. J Nat Prod 84(4), 1403-1408.
Gressler M, Löhr NA, Schäfer T, Lawrinowitz S, Seibold PS, Hoffmeister D (2021) Mind the mushroom: natural product biosynthetic genes and enzymes of Basidiomycota. Nat Prod Rep 38(4), 702-722. (Review)
Herkersdorf S, Krüger T, Wein P, Löffler S, Fontaine T, Gressler M, Hertweck C, Brakhage AA, Hoffmeister D (2021) Bacterial cell wall-degrading enzymes induce basidiomycete natural product biosynthesis. Environ Microbiol 23(8), 4360-4371.
Lenz C, Dörner S, Sherwood A, Hoffmeister D (2021) Structure elucidation and spectroscopic analysis of chromophores produced by oxidative psilocin dimerization. Chemistry 27(47), 12166-12171.
Lenz C, Sherwood A, Kargbo R, Hoffmeister D (2021) Taking different roads: L-Tryptophan as the origin of psilocybe natural products. ChemPlusChem 86(1), 28-35.
Mohr JF, Baldeweg F, Deicke M, Morales-Reyes CF, Hoffmeister D, Wichard T (2021) Frankobactin metallophores produced by nitrogen-fixing Frankia actinobacteria function in toxic metal sequestration. J Nat Prod 84(4), 1216-1225.
Blei F, Dörner S, Fricke J, Baldeweg F, Trottmann F, Komor AJ, Meyer F, Hertweck C, Hoffmeister D (2020) Simultaneous production of psilocybin and a cocktail of β-carboline monoamine oxidase inhibitors in ‘magic’ mushrooms. Chem Eur J 26(3), 729-734.
Demmler R, Fricke J, Dörner S, Gressler M, Hoffmeister D (2020) S-adenosyl-L-methionin salvage impacts psilocybin formation in 'magic' mushrooms. ChemBioChem 21(9), 1364-1371.
Fricke J, Kargbo R, Regestein L, Lenz C, Peschel G, Rosenbaum MA, Sherwood A, Hoffmeister D (2020) Scalable hybrid synthetic/biocatalytic route to psilocybin. Chem Eur J 37(26), 8281-8285.
Lenz C, Wick J, Braga D, Garcia-Altares M, Lackner G, Hertweck C, Gressler M, Hoffmeister D (2020) Injury-triggered blueing reactions of Psilocybe "magic" mushrooms. Angew Chem Int Ed 59(4), 1450-1454.