(2008)
The Aspergillus nidulans enzyme TdiB catalyzes prenyltransfer to the precursor of bioactive asterriquinones.
Fungal Genet Biol 45,
302-309.
Dirk Hoffmeister
Pharmaceutical Microbiology · Head +49 3641 9-49850 dirk.hoffmeister@leibniz-hki.deCurriculum vitae
Main Research Areas
- Biochemical and genetic basis of fungal natural product biosyntheses
- Natural products of basidiomycetes and Ralstonia solanacearum
- Microbial nonribosomal peptide synthetases
Professional Career
| 2014- | Full Professor for Pharmaceutical Microbiology, FSU Jena and HKI Jena |
| 2009-2014 | Associate Professor for Pharmaceutical Biology, FSU Jena and head of the associated department Pharmaceutical Biology at the HKI Jena |
| 2007-2009 | Assistant Professor (tenure track) University of Minnesota, Saint Paul, MN, USA |
| 2008 | Habilitation in Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University Freiburg |
| 2004-2007 | Junior Group Leader, Institute for Pharmacy, Albert-Ludwigs-University, Freiburg |
| 2002-2004 | Postdoc, University of Wisconsin, Madison, WI, USA (DFG-fellowship) |
| 2002 | Dr. rer. nat., Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University, Freiburg |
| 1998 | Diploma in biology at the Eberhard-Karls-University, Tübingen |
Awards · Appointments · Scientific Activities
| Since 2020 | Head of the Institute for Pharmacy, FSU Jena |
| 2016-2019 | Dean for Study Affairs in the Faculty of Biology and Pharmacy, FSU Jena |
| 2013-2016 | Scientific advisory board, Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM). |
Publications
(2007)
Accurate prediction of the Aspergillus nidulans terrequinone gene cluster boundaries using the transcriptional regulator LaeA.
Fungal Genet Biol 44,
1134-1145.
(2007)
Natural products of filamentous fungi: enzymes, genes, and their regulation.
Nat Prod Rep 24,
393-416.
(2007)
Fungal genetics, genomics, and secondary metabolites in pharmaceutical sciences.
Planta Med 73,
103-115.
(2007)
A one-pot chemoenzymatic synthesis for the universal precursor of antidiabetes and antiviral bis-indolylquinones.
Chem Biol 14,
635-644.
(2006)
Genomic mining for Aspergillus natural products.
Chem Biol 13,
31-37.
(2005)
Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase.
J Biol Chem 280,
22508-22514.
(2005)
Generation of novel landomycins M and O through targeted gene disruption.
Chembiochem 6,
675-678.
(2004)
The glycosyltransferase UrdGT2 catalyzes both C- and O-glycosidic sugar transfers.
Angew Chem Int Ed Engl 43,
2962-2965.
(2004)
Mechanistic implications of Escherichia coli galactokinase structure-based engineering.
Chembiochem 5,
989-992.
