(2021)
Frankobactin metallophores produced by nitrogen-fixing Frankia actinobacteria function in toxic metal sequestration.
J Nat Prod 84(4),
1216-1225.
Dirk Hoffmeister
Pharmaceutical Microbiology · Head +49 3641 9-49850 dirk.hoffmeister@leibniz-hki.deCurriculum vitae
Main Research Areas
- Biochemical and genetic basis of fungal natural product biosyntheses
- Natural products of basidiomycetes and Ralstonia solanacearum
- Microbial nonribosomal peptide synthetases
Professional Career
| 2014- | Full Professor for Pharmaceutical Microbiology, FSU Jena and HKI Jena |
| 2009-2014 | Associate Professor for Pharmaceutical Biology, FSU Jena and head of the associated department Pharmaceutical Biology at the HKI Jena |
| 2007-2009 | Assistant Professor (tenure track) University of Minnesota, Saint Paul, MN, USA |
| 2008 | Habilitation in Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University Freiburg |
| 2004-2007 | Junior Group Leader, Institute for Pharmacy, Albert-Ludwigs-University, Freiburg |
| 2002-2004 | Postdoc, University of Wisconsin, Madison, WI, USA (DFG-fellowship) |
| 2002 | Dr. rer. nat., Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University, Freiburg |
| 1998 | Diploma in biology at the Eberhard-Karls-University, Tübingen |
Awards · Appointments · Scientific Activities
| Since 2020 | Head of the Institute for Pharmacy, FSU Jena |
| 2016-2019 | Dean for Study Affairs in the Faculty of Biology and Pharmacy, FSU Jena |
| 2013-2016 | Scientific advisory board, Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM). |
Publications
(2020)
Simultaneous production of psilocybin and a cocktail of β-carboline monoamine oxidase inhibitors in ‘magic’ mushrooms.
Chem Eur J 26(3),
729-734.
(2020)
S-adenosyl-L-methionin salvage impacts psilocybin formation in 'magic' mushrooms.
ChemBioChem 21(9),
1364-1371.
(2020)
Scalable hybrid synthetic/biocatalytic route to psilocybin.
Chem Eur J 37(26),
8281-8285.
(2020)
Injury-triggered blueing reactions of Psilocybe "magic" mushrooms.
Angew Chem Int Ed 59(4),
1450-1454.
(2020)
The Laetiporus polyketide synthase LpaA produces a series of antifungal polyenes.
J Antibiot 73(10),
711-720.
(2020)
Secretion of iron(III)-reducing metabolites during protein acquisition by the ectomycorrhizal fungus Paxillus involutus.
Microorganisms 9(1),
E35.
(2019)
Diketopiperazine formation in fungi requires dedicated cyclization and thiolation domains.
Angew Chem Int Ed 58(41),
14589-14593.
(2019)
A genomics perspective on natural product biosynthesis in plant pathogenic bacteria.
Nat Prod Rep 36(2),
307-325.
(Review)
(2019)
Diversity and bioactivity of Armillaria sesquiterpene aryl ester natural products.
Mycol Prog 18(8),
1027-1037.
