Curriculum vitae

Main Research Areas
  • Biochemical and genetic basis of fungal natural product biosyntheses
  • Natural products of basidiomycetes and Ralstonia solanacearum
  • Microbial nonribosomal peptide synthetases
Professional Career
2014- Full Professor for Pharmaceutical Microbiology, FSU Jena and HKI Jena
2009-2014 Associate Professor for Pharmaceutical Biology, FSU Jena and head of the associated department Pharmaceutical Biology at the HKI Jena
2007-2009 Assistant Professor (tenure track) University of Minnesota, Saint Paul, MN, USA
2008 Habilitation in Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University Freiburg
2004-2007 Junior Group Leader, Institute for Pharmacy, Albert-Ludwigs-University, Freiburg
2002-2004 Postdoc, University of Wisconsin, Madison, WI, USA (DFG-fellowship)
2002 Dr. rer. nat., Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University, Freiburg
1998 Diploma in biology at the Eberhard-Karls-University, Tübingen
Awards · Appointments · Scientific Activities
Since 2020 Head of the Institute for Pharmacy, FSU Jena
2016-2019 Dean for Study Affairs in the Faculty of Biology and Pharmacy, FSU Jena
2013-2016 Scientific advisory board, Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM).

Publications

Kalb D, Gressler J, Hoffmeister D (2016) Active-Site Engineering Expands the Substrate Profile of the Basidiomycete L-Tryptophan Decarboxylase CsTDC. ChemBioChem 17, 132-136.
Kalb D, Heinekamp T, Schieferdecker S, Nett M, Brakhage AA, Hoffmeister D (2016) An Iterative O-Methyltransferase Catalyzes 1,11-Dimethylation of Aspergillus fumigatus Fumaric Acid Amides. ChemBioChem 17, 1813-1817.
Schlegel M, Münsterkötter M, Güldener U, Bruggmann R, Duo A, Hainaut M, Henrissat B, Sieber CM, Hoffmeister D, Grünig CR (2016) Globally distributed root endophyte Phialocephala subalpina links pathogenic and saprophytic lifestyles BMC Genomics 17, 1015.
Schwenk D, Brandt P, Blanchette R, Nett M, Hoffmeister D (2016) Unexpected metabolic versatility in a combined fungal fomannoxin/vibralactone biosynthesis. J. Nat. Prod. 79, 1407-1414.
Shah F, Nicolas C, Bentzer J, Ellström M, Smits M, Rineau F, Canbäck B, Floudas D, Carleer R, Lackner G, Braesel J, Hoffmeister D, Henrissat B, Ahrén D, Johansson T, Hibbett DS, Martin F, Persson P, Tunlid A (2016) Ectomycorrhizal fungi decompose soil organic matter using oxidative mechanisms adapted from saprotrophic ancestors. New Phytol 209, 1705-1719.
Shah F, Schwenk D, Nicolas C, Persson P, Hoffmeister D, Tunlid A (2016) Involutin is a Fe3+ reductant Secreted by the Ectomycorrhizal Fungus Paxillus involutus during Fenton-based Decomposition of Organic Matter. Appl Environ Microbiol 81, 8427-8433.
Tauber JP, Schroeckh V, Shelest E, Brakhage AA, Hoffmeister D (2016) Bacteria induce pigment formation in the basidiomycete Serpula lacrymans. Environ Microbiol 18, 5218-5227.
Wick J, Heine D, Lackner G, Misiek M, Tauber J, Jagusch H, Hertweck C, Hoffmeister D (2016) A fivefold parallelized biosynthetic process secures chlorination of Armillaria mellea (honey mushroom) toxins. Appl Environ Microbiol 82, 1196-1204.
Braesel J, Götze S, Shah F, Heine D, Tauber J, Hertweck C, Tunlid A, Stallforth P, Hoffmeister D (2015) Three redundant synthetases secure redox-active pigment production in the basidiomycete Paxillus involutus. Chem Biol 22, 1325-1334.
Kalb D, Heinekamp T, Lackner G, Scharf DH, Dahse HM, Brakhage AA, Hoffmeister D (2015) Genetic engineering activates biosynthesis of aromatic fumaric acid amides in the human pathogen Aspergillus fumigatus. Appl Environ Microbiol 81, 1594-1600.