Dr. Sarah Niehs

Alumni

Publications

Büttner H*, Niehs SP*, Vandelannoote K, Cseresnyés Z, Dose B, Richter I, Gerst R, Figge MT, Stinear TP, Pidot SJ, Hertweck C# (2021) Bacterial endosymbionts protect beneficial soil fungus from nematode attack. Proc Natl Acad Sci U S A 118(37), e2110669118.
Dose B, Niehs SP, Scherlach K*, Shahda S, Flórez LV#, Kaltenpoth M, Hertweck C (2021) Biosynthesis of sinapigladioside, an antifungal isothiocyanate from Burkholderia symbionts. Chembiochem 22(11), 1920-1924.
Dose B, Thongkongkaew T, Zopf D, Kim HJ, Bratovanov EV, García-Altares M, Scherlach K, Kumpfmüller J, Ross C, Hermenau R, Niehs S, Silge A, Hniopek J, Schmitt M, Popp J, Hertweck C (2021) Multimodal molecular imaging and identification of bacterial toxins causing mushroom soft rot and cavity disease. Chembiochem ,
Mahler L , Niehs SP, Martin K, Weber T, Scherlach K, Hertweck C, Roth M, Rosenbaum MA (2021) Highly parallelized droplet cultivation and prioritization of antibiotic producers from natural microbial communities. eLife 10, e64774.
Dose B, Ross C, Niehs SP, Scherlach K, Bauer JP, Hertweck C (2020) Food-poisoning bacteria employ a citrate synthase and a type II NRPS to synthesize bolaamphiphilic lipopeptide antibiotics. Angew Chem Int Ed 59(48), 21535-21540.
Niehs SP, Dose B, Richter S, Pidot SJ, Dahse HM, Stinear TP, Hertweck C (2020) Mining symbionts of spider-transmitted fungus illuminates uncharted biosynthetic pathways to cytotoxic benzolactones. Angew Chem Int Ed 59(20), 7766-7771.
Niehs SP, Kumpfmüller J, Dose B, Little RF, Ishida K, Florez LV, Kaltenpoth M, Hertweck C (2020) Insect-associated bacteria assemble the antifungal butenolide gladiofungin by non-canonical polyketide chain termination. Angew Chem Int Ed 59(51), 23122-23126.
Niehs SP, Dose B, Scherlach K, Pidot SJ, Stinear TP, Hertweck C (2019) Genome mining reveals endopyrroles from a nonribosomal peptide assembly line triggered in fungal-bacterial symbiosis. ACS Chem Biol 14(8), 1811-1818.
Dose B, Niehs SP, Scherlach K, Flórez LV, Kaltenpoth M, Hertweck C (2018) Unexpected bacterial origin of the antibiotic icosalide: Two-tailed depsipeptide assembly in multifarious Burkholderia symbionts. ACS Chem Biol 13(9), 2414-2420.
Niehs SP, Dose B, Scherlach K, Roth M, Hertweck C (2018) Genomics-driven discovery of a symbiont-specific cyclopeptide from bacteria residing in the rice seedling blight fungus. ChemBioChem 19(20), 2167-2172.