(2014)
Automated detection of circulating tumor cells with naive Bayesian classifiers.
Cytometry A 85(6),
501-511.
Curriculum vitae
Main Research Areas
- Host-pathogen interaction on human pathogenic fungi
- Automated processing of microscopic images
- Spatiotemporal computer simulations of agent-based infection models
Professional Career
| since 2021 | Professor (W3) for Applied Systems Biology, Friedrich Schiller University Jena |
| since 2011 | Head of Research Group Applied Systems Biology, Leibniz-HKI |
| 2011-2021 | Professor (W2) for Applied Systems Biology, Friedrich Schiller University Jena |
| 2005-2010 | Junior Fellow in Theoretical Immunology at the Frankfurt Institute for Advanced Studies (FIAS) of the Goethe University Frankfurt |
| 2001-2005 | Research assistant in Computer Physics at the University Groningen (NL) |
| 2000 | Dr. rer. nat. in Physics at the University Groningen (NL) |
| 1995 | Diploma in Physics at the University Dortmund |
Awards · Appointments · Scientific Activities
Awards
| 2011 - 2017 | Adjunct Fellow at Frankfurt Institute for Advanced Studies (FIAS) |
Scientific Activities and Functions
| since 2021 | Deputy Coordinator of the Jena School for Microbial Communication |
| since 2019 | Coordinator of Research Area C – Data Synopsis in the Excellence Cluster “Balance of the Microverse” |
| Member of the Management Board of the Microverse Imaging Center in the Excellence Cluster “Balance of the Microverse” | |
| since 2019 | Speaker of Leibniz ScienceCampus “InfectoOptics” |
| since 2019 | Editor: Scientific Reports |
| since 2017 | Ombudsperson at the Leibniz Institute for Natural Product Research and Infection Biology |
| since 2017 | PI and member of the DFG-Collaborative Research Center 1278 PolyTarget |
| since 2017 | Editor: Cytometry A |
| since 2015 | Member: Jena Center for Soft Matter |
| since 2015 | Member: Michael Stifel Center for Data-Driven and Simulation Science |
| since 2014 | PI and member of the DFG-Collaborative Research Center 124 FungiNet |
| since 2014 | Editor: Computational and Mathematical Models in Medicine |
| since 2012 | Organizer: Biennial international symposium on “Image-based Systems Biology” (IbSB) |
| since 2011 | Organizer: Biennial international symposium on “Systems Biology of Microbial Infection” (SBMI) |
| since 2011 | Member: International Leibniz Research School for Microbial and Biomolecular Interactions |
| since 2011 | Member: Jena School for Microbial Communication |
Publications
(2013)
Naive B-cell trafficking is shaped by local chemokine availability and LFA-1-independent stromal interactions.
Blood 121(20),
4101-4109.
(2013)
Quality control of mitochondria during aging: is there a good and a bad side of mitochondrial dynamics?
Bioessays 35(4),
314-322.
(2013)
Automated characterization and parameter-free classification of cell tracks based on local migration behavior.
PLOS ONE 8(12),
e80808.
(2013)
Real-time image processing for label-free enrichment of Actinobacteria cultivated in picolitre droplets.
Lab Chip 13(18),
3707-3713, *authors contributed equally.
(2013)
Germinal center B cells govern their own fate via antibody feedback.
J Exp Med 210(3),
457-464.
(2012)
Deceleration of fusion-fission cycles improves mitochondrial quality control during aging.
PLOS Comput Biol 8(6),
e1002576.
(2012)
Systems biology of microbial infection.
Front Microbiol 3,
328.
(2012)
Image-based systems biology: A quantitative approach to elucidate the kinetics of fungal morphologies and virulence.
In: Highlight Papers of the German Conference on Bioinformatics 2012
German Conference on Bioinformatics, Jena, GCB.
(2012)
Agent-based modeling approach of immune defense against spores of opportunistic human pathogenic fungi.
Front Microbiol 3,
129.
