Marc Thilo Figge

Prof. Dr. Marc Thilo Figge

Applied Systems Biology +49 3641 532-1416 thilo.figge@leibniz-hki.de

Curriculum vitae

Main Research Areas
  • Host-pathogen interaction of human pathogenic fungi
  • Automated processing of microscopic images and spectroscopy data
  • Spatiotemporal computer simulations of agent-based infection models
Professional Career
since 2021 Professor (W3) for Applied Systems Biology, Friedrich Schiller University Jena
since 2011 Head of Research Group Applied Systems Biology, Leibniz-HKI
2011-2021 Professor (W2) for Applied Systems Biology, Friedrich Schiller University Jena
2005-2010 Junior Fellow in Theoretical Immunology at the Frankfurt Institute for Advanced Studies (FIAS) of the Goethe University Frankfurt
2001-2005 Research assistant in Computer Physics at the University Groningen (NL)
2000 Dr. rer. nat. in Physics at the University Groningen (NL)
1995 Diploma in Physics at the University Dortmund
Awards · Appointments · Scientific Activities

Awards

2011 - 2017 Adjunct Fellow at Frankfurt Institute for Advanced Studies (FIAS)

Appointments and Scientific Activities

since 2023 Board Member and Coordinator of Task Area “Bioimage Informatics” in the DFG-funded national research data management initiative “NFDI4Bioimage”
since 2023 Board Member and PI in the DFG-Research Training School RTG 2723 – “Materials-Microbes-Microenvironments”
since 2023 Board Member of the Beutenberg Campus e.V. “Life Science meets Physics”
since 2023 Editor: PLOS Complex Systems
since 2023 Editor: Biological Imaging
since 2022 Coordinator of Basic Technology 3 in the BMBF-funded “Leibniz Center for Photonics in Infection Research”
since 2022 Coordinator of the BMBF-funded "Multi-Model-Simulator Project” in the funding line “Computational Life Sciences”
since 2021 Deputy Coordinator of the "Jena School for Microbial Communication"
since 2019 Coordinator of Research Area C – Data Synopsis in the Excellence Cluster “Balance of the Microverse”
since 2019 Member of the Management Board of the Microverse Imaging Center in the Excellence Cluster “Balance of the Microverse”
since 2019 Speaker and PI of Leibniz ScienceCampus “InfectoOptics”
since 2019 Editor: Scientific Reports
since 2017 Ombudsperson at the Leibniz Institute for Natural Product Research and Infection Biology
since 2017 PI and member of the DFG-Collaborative Research Center 1278 PolyTarget
since 2017 Editor: Cytometry A
since 2015 Member: Jena Center for Soft Matter
since 2015 Member: Michael Stifel Center for Data-Driven and Simulation Science
since 2014 PI and member of the DFG-Collaborative Research Center 124 FungiNet
since 2012 Organizer: Biennial international symposium on “Image-based Systems Biology” (IbSB)
since 2011 Organizer: Biennial international symposium on “Systems Biology of Microbial Infection” (SBMI)
since 2011 Faculty member and PI in the "International Leibniz Research School for Microbial and Biomolecular Interactions"
since 2011 Faculty member and PI in the "Jena School for Microbial Communication"

Publications

Figge MT (2009) Optimization of immunoglobulin substitution therapy by a stochastic immune response model. PLOS ONE 4(5), e5685.
Figge MT, Meyer-Hermann M (2009) Modeling receptor-ligand binding kinetics in immunological synapse formation. The European Physical Journal D 51(1), 153-160.
Meyer-Hermann M, Figge MT, Straub RH (2009) Mathematical modeling of the circadian rhythm of key neuroendocrine-immune system players in rheumatoid arthritis: a systems biology approach. Arthritis Rheum 60(9), 2585-2594.
Meyer-Hermann M, Figge MT, Toellner KM (2009) Germinal centres seen through the mathematical eye: B-cell models on the catwalk. Trends Immunol 30(4), 157-164.
Figge MT, Garin A, Gunzer M, Kosco-Vilbois M, Toellner KM, Meyer-Hermann M (2008) Deriving a germinal center lymphocyte migration model from two-photon data. J Exp Med 205(13), 3019-3029.
Figge MT, Meyer-Hermann M (2006) Geometrically repatterned immunological synapses uncover formation mechanisms. PLOS Comput Biol 2(11), e171.
Michielsen K, Figge MT, De Raedt H, De Hossen JTM (2004) Molecular dynamics simulation of nanoindentation In: Computer simulation studies incondensed-matter physics XVI pp. 250-255.Springer-Verlag, Berlin Heidelberg. ISBN: 978-3-642-63923.
De Raedt H, Kole JS, Michielsen K, Figge MT (2003) Unified framework for numerical methods to solve the time-dependent Maxwell equations. Computer Physics Communication 156, 43-61.
De Raedt H, Michielsen K, Kole JS, Figge MT (2003) Chebyshev method to solve the time-dependent Maxwell equations. In: Computer simulation studies in condensed-matter physics XV, pp. 211-215.Springer-Verlag Berlin Heidelberg.
De Raedt H, Michielsen K, Kole JS, Figge MT (2003) One-step finite-difference time-domain algorithm to solve the Maxwell equations. Phys Rev E Stat Nonlin Soft Matter Phys 67(5 Pt 2), 056706.

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