(2023)
IMFSegNet: Cost-effective and objective quantification of intramuscular fat in histological sections by deep learning.
Comput Struct Biotechnol J 21,
2696-3704.
Curriculum vitae
Main Research Areas
- Host-pathogen interaction on human pathogenic fungi
- Automated processing of microscopic images
- Spatiotemporal computer simulations of agent-based infection models
Professional Career
| since 2021 | Professor (W3) for Applied Systems Biology, Friedrich Schiller University Jena |
| since 2011 | Head of Research Group Applied Systems Biology, Leibniz-HKI |
| 2011-2021 | Professor (W2) for Applied Systems Biology, Friedrich Schiller University Jena |
| 2005-2010 | Junior Fellow in Theoretical Immunology at the Frankfurt Institute for Advanced Studies (FIAS) of the Goethe University Frankfurt |
| 2001-2005 | Research assistant in Computer Physics at the University Groningen (NL) |
| 2000 | Dr. rer. nat. in Physics at the University Groningen (NL) |
| 1995 | Diploma in Physics at the University Dortmund |
Awards · Appointments · Scientific Activities
Awards
| 2011 - 2017 | Adjunct Fellow at Frankfurt Institute for Advanced Studies (FIAS) |
Scientific Activities and Functions
| since 2021 | Deputy Coordinator of the Jena School for Microbial Communication |
| since 2019 | Coordinator of Research Area C – Data Synopsis in the Excellence Cluster “Balance of the Microverse” |
| Member of the Management Board of the Microverse Imaging Center in the Excellence Cluster “Balance of the Microverse” | |
| since 2019 | Speaker of Leibniz ScienceCampus “InfectoOptics” |
| since 2019 | Editor: Scientific Reports |
| since 2017 | Ombudsperson at the Leibniz Institute for Natural Product Research and Infection Biology |
| since 2017 | PI and member of the DFG-Collaborative Research Center 1278 PolyTarget |
| since 2017 | Editor: Cytometry A |
| since 2015 | Member: Jena Center for Soft Matter |
| since 2015 | Member: Michael Stifel Center for Data-Driven and Simulation Science |
| since 2014 | PI and member of the DFG-Collaborative Research Center 124 FungiNet |
| since 2014 | Editor: Computational and Mathematical Models in Medicine |
| since 2012 | Organizer: Biennial international symposium on “Image-based Systems Biology” (IbSB) |
| since 2011 | Organizer: Biennial international symposium on “Systems Biology of Microbial Infection” (SBMI) |
| since 2011 | Member: International Leibniz Research School for Microbial and Biomolecular Interactions |
| since 2011 | Member: Jena School for Microbial Communication |
Publications
(2023)
Sodium thiosulfate refuels the hepatic antioxidant pool reducing ischemia-reperfusion-induced liver injury.
Free Radic Biol Med 204,
151-160.
(2023)
Surrogate infection model predicts optimal alveolar macrophage number for clearance of Aspergillus fumigatus infections.
NPJ Syst Biol Appl 9,
12.
(2022)
Automated characterisation of neutrophil activation phenotypes in ex vivo human Candida blood infections.
Comput Struct Biotechnol J 20,
2297-2308.
(2022)
Acceptance of different self-sampling methods for semiweekly SARS-CoV-2 testing in asymptomatic children and childcare workers at German Day Care Centers: A nonrandomized controlled trial.
JAMA Netw Open 5(9),
e2231798.
(2022)
Feasibility of SARS-CoV-2 surveillance testing among children and childcare workers at German Day Care Centers: A nonrandomized controlled trial.
JAMA Netw Open 5(1),
e2142057.
(2022)
Invasive aspergillosis-on-chip: A quantitative treatment study of human Aspergillus fumigatus infection.
Biomaterials 283,
121420.
(2022)
Spatial quantification of clinical biomarker pharmacokinetics through deep learning-based segmentation and signal-oriented analysis of MSOT data.
Photoacoustics 26,
100361.
(2022)
Toxin-producing endosymbionts shield pathogenic fungus against micropredators.
mBio 13(5),
e0144022.
(2022)
Research data management for bioimaging: The 2021 NFDI4BIOIMAGE community survey.
F1000Research 11,
638.
