(2023)
Biosynthetic incorporation of fluorinated amino acids into the nonribosomal peptide gramicidin S.
RSC Chem Biol 4,
692-697.

Dr Hajo Kries
Biosynthetic Design of Natural Products · Head +49 3641 532 1735 hajo.kries@leibniz-hki.deCurriculum vitae
Professional Career
2023 | Substitute Professor W3 Organic Chemistry I, University of Bayreuth |
since 2016 | Junior Group Leader, Leibniz Institute for Natural Product Research and Infection Biology (Hans-Knöll-Institute), Jena |
2014-2016 | Postdoc, John Innes Centre, Norwich (UK), with Prof. Sarah E. O'Connor |
2009-2014 | PhD "Tailor-made biocatalysts by enzyme design, redesign, and directed evolution" at ETH Zurich with Prof. Donald Hilvert |
2007-2009 | MSc in Chemistry, ETH Zurich |
2006-2007 | BSc in Biochemistry, University of Geneva |
2003-2006 | Studies of Biochemistry, University of Jena |
2002 | Abitur at the Gymnasium Heide-Ost |
Awards · Appointments · Scientific Activities
2021 | Max Buchner Fellowship, DECHEMA |
2020 | Medac Research Prize |
2019 | FCI material cost allowances |
2017-2019 | Fellowship of the Daimler and Benz Foundation |
2015-2016 | Marie Skłodowska-Curie postdoctoral fellowship (H2020), project 658155 |
2015 | Friedrich-Weygang-Preis, awarded by the Max-Bergmann-Kreis |
2015 | ETH Medal for the PhD thesis |
2014-2015 | Early Postdoc.Mobility fellowship of the Swiss National Science Foundation (SNSF) |
2011-2014 | PhD Fellowship of the Stipendienfonds der Schweizerischen Chemischen Industrie (SSCI) |
2010-2012 | PhD Fellowship of the German Academic Scholarship Foundation |
2008-2009 | Oskar Jeger Fellowship for master studies (ETH Zurich) |
2008 | Novartis Master Fellowship |
2007-2009 | DAAD grant for foreign studies |
2005-2009 | Fellowship of the German Academic Scholarship Foundation |
Publications
(2023)
Directed evolution of piperazic acid incorporation by a nonribosomal peptide synthetase.
Angew Chem Int Ed Engl 62(35),
e202304843.
(2023)
Biomimetic engineering of nonribosomal peptide synthesis.
Biochem Soc Trans 51(4),
1521-1532.
(Review)
(2022)
Proof-reading thioesterase boosts activity of engineered nonribosomal peptide synthetase.
ACS Chem Biol 17(9),
2382-2388.
(2022)
Total synthesis and functional evaluation of IORs, sulfonolipid-based inhibitors of cell differentiation in Salpingoeca rosetta.
Angew Chem Int Ed 61(41),
e202209105.
(2022)
Defining a nonribosomal specificity code for design.
bioRxiv
[Preprint]
(2022)
Pathogenic bacteria remodel central metabolic enzyme to build a cyclopropanol warhead.
Nat Chem 14(8),
884-890.
(2022)
Macrophage-targeting oligopeptides from Mortierella alpina.
Chem Sci 13(31),
9091-9101.
(2021)
Engineered nonribosomal peptide synthetase shows opposite amino acid loading and condensation specificity.
ACS Catal 11(14),
8692-8700.
(2020)
Engineering DNA-templated nonribosomal peptide synthesis.
Cell Chem Biol S2451-9456(20),
30433-5.