Curriculum vitae

Professional Career


2023 Substitute Professor W3 Organic Chemistry I, University of Bayreuth
since 2016 Junior Group Leader, Leibniz Institute for Natural Product Research and Infection Biology (Hans-Knöll-Institute), Jena
2014-2016 Postdoc, John Innes Centre, Norwich (UK), with Prof. Sarah E. O'Connor
2009-2014 PhD "Tailor-made biocatalysts by enzyme design, redesign, and directed evolution" at ETH Zurich with Prof. Donald Hilvert
2007-2009 MSc in Chemistry, ETH Zurich
2006-2007 BSc in Biochemistry, University of Geneva
2003-2006 Studies of Biochemistry, University of Jena
2002 Abitur at the Gymnasium Heide-Ost
Awards · Appointments · Scientific Activities
2021 Max Buchner Fellowship, DECHEMA
2020 Medac Research Prize
2019 FCI material cost allowances
2017-2019 Fellowship of the Daimler and Benz Foundation
2015-2016 Marie Skłodowska-Curie postdoctoral fellowship (H2020), project 658155
2015 Friedrich-Weygang-Preis, awarded by the Max-Bergmann-Kreis
2015 ETH Medal for the PhD thesis
2014-2015 Early Postdoc.Mobility fellowship of the Swiss National Science Foundation (SNSF)
2011-2014 PhD Fellowship of the Stipendienfonds der Schweizerischen Chemischen Industrie (SSCI)
2010-2012 PhD Fellowship of the German Academic Scholarship Foundation
2008-2009 Oskar Jeger Fellowship for master studies (ETH Zurich)
2008 Novartis Master Fellowship
2007-2009 DAAD grant for foreign studies
2005-2009 Fellowship of the German Academic Scholarship Foundation


Little RF, Trottmann F, Hashizume H, Preissler M, Unger S, Sawa R, Kries H, Pidot S, Igarashi M, Hertweck C (2024) Analysis of the valgamicin biosynthetic pathway reveals a general mechanism for cyclopropanol formation across diverse natural product scaffolds. ACS Chem Biol 19(3), 660-668.
Peng H, Schmiederer J, Chen X, Panagiotou G, Kries H# (2024) Controlling substrate- and stereospecificity of condensation domains in nonribosomal peptide synthetases. ACS Chem Bio 19(3), 599-606.
Kries H, Trottmann F, Hertweck C (2023) Novel biocatalysts from specialized metabolism. Angew Chem Int Ed Engl 63(4), e202309284. (Review)
Müll M, Pourmasoumi F, Wehrhan L, Nosovska O, Stephan P, Zeihe H, Vilotijevic I, Keller BG, Kries H (2023) Biosynthetic incorporation of fluorinated amino acids into the nonribosomal peptide gramicidin S. RSC Chem Biol 4(9), 692-697.
Pourmasoumi F,* Hengoju S,* Beck K, Stephan P, Klopfleisch L, Hoernke M, Rosenbaum MA, Kries H (2023) Analysing megasynthetase mutants at high throughput using droplet microfluidics. Chembiochem 24(24), e202300680.
Stephan P, Langley C, Winkler D, Basquin J, Caputi L, O'Connor SE, Kries H (2023) Directed evolution of piperazic acid incorporation by a nonribosomal peptide synthetase. Angew Chem Int Ed Engl 62(35), e202304843.
Zhang K, Kries H (2023) Biomimetic engineering of nonribosomal peptide synthesis. Biochem Soc Trans 51(4), 1521-1532. (Review)
Pourmasoumi F,* De S,* Peng H, Trottmann F, Hertweck C, Kries H (2022) Proof-reading thioesterase boosts activity of engineered nonribosomal peptide synthetase. ACS Chem Biol 17(9), 2382-2388.
Raguž L, Peng CC, Rutaganira FUN, Krüger T, Stanišić A, Jautzus T, Kries H, Kniemeyer O, Brakhage AA, King N, Beemelmanns C (2022) Total synthesis and functional evaluation of IORs, sulfonolipid-based inhibitors of cell differentiation in Salpingoeca rosetta. Angew Chem Int Ed 61(41), e202209105.
Stanišić A, Svensson CM, Ettelt U, Kries H# (2022) Defining a nonribosomal specificity code for design. bioRxiv [Preprint]