(2022) Lactobacillus rhamnosus colonisation antagonizes Candida albicans by forcing metabolic adaptations that compromise pathogenicity. Nat Commun 13(1), 3192.
Main Research Areas
- Molecular links between metabolism and virulence in pathogenic Candida spp.
- Role of intra and inter-species metabolic signals in establishment of microbial communities
- Candidiasis infection models
|since 2016||JRG leader, JRG Host Fungal Interfaces, ZIK Septomics, Friedrich Schiller University Jena|
|2014-2016||Assistant Professor-Research, University of Texas Health Science Center at Houston, Houston, TX, USA|
|2012-2016||Adjunct Faculty, University of Houston-Downtown, Houston, TX, USA|
|2013-2014||Senior Research Associate, University of Texas Health Science Center at Houston, Houston, TX, USA|
|2007-2013||Post-doctoral fellow, University of Texas Health Science Center at Houston, Houston, TX, USA|
|2007||Ph.D., State University of New York at Buffalo, Buffalo, NY, USA|
|2006-2007||Research Assistant (Postdoc), Ottawa Health Research institute, Centre for Cancer Research, Ottawa, ON, Canada|
|2002-2006||Research Assistant, State University of New York at Buffalo, Department of Oral Biology, Buffalo, NY, USA|
|2004||M.Sc., State University of New York at Buffalo, Buffalo, NY, USA|
|2004||Research Assistant, State University of New York at Buffalo, Physiology Department Buffalo, NY, USA|
|2001||M.Sc., Sofia University, Sofia, Bulgaria|
Awards · Appointments · Scientific Activities
|since 2021||Editor, Microbiology Spectrum|
|since 2018||Editor, Frontiers in Microbiology|
|2014||Judge Travel Grant, Annual Biomedical Research Conference for Minority Students, San Antonio, TX, USA|
|2014||ISHAM Young Fellow Travel Award, American society for Microbiology, 12th ASM Conference on Candida and Candidiasis, New Orleans, LA, USA|
|2011||Office of the Dean of McGovern Medical School Postdoctoral Fellow Travel Grant, University of Texas Health Science Center Houston, Houston, TX, USA|
(2022) Impaired amino acid uptake leads to global metabolic imbalance of Candida albicans biofilms. NPJ Biofilms Microbiomes 8(1), 78.
(2022) Candida albicans SR-like protein kinases regulate different cellular processes: Sky1 is involved in control of ion homeostasis, while Sky2 is important for dipeptide utilization. Front Cell Infect Microbiol 12, 850531.
(2022) Systematic metabolic profiling identifies de novo sphingolipid synthesis as hypha associated and essential for Candida albicans filamentation. mSystems 7(6), e0053922.
(2022) GNP2 encodes a high-specificity proline permease in Candida albicans. mBio 13(1), e0314221.
(2021) Metabolic modeling predicts specific gut bacteria as key determinants for Candida albicans colonization levels. ISME J 15(5), 1257-1270.
(2020) The transcription factor Stp2 is important for Candida albicans biofilm establishment and sustainability. Front Microbiol 11, 794.
(2020) Catch the wave: Metabolomic analyses in human pathogenic fungi. PLOS Pathog 16(8), e1008757. (Review)
(2020) Clinical Candida albicans vaginal isolates and a laboratory strain show divergent behaviors during macrophage interactions. mSphere 5(4), e00393-20.
(2020) Ahr1 and Tup1 contribute to the transcriptional control of virulence-associated genes in Candida albicans. mBio 11(2), e00206-20.