(2012)
Candida albicans dimorphism as a therapeutic target.
Expert Rev Anti Infect Ther 10(1),
85-93.
(Review)
Prof. Dr. Ilse Denise Jacobsen
Microbial Immunology · Head Deputy Director +49 3641 532-1223 ilse.jacobsen@leibniz-hki.deCurriculum vitae
Main Research Areas
- Immunology and infection biology of pathogenic fungi
- In vivo and ex vivo infection models
- Mucosal pathogen-host-interaction
Professional Career
since 2014 | Professor for Microbial Immunology, FSU Jena |
since 2013 | Head of the research group "Microbial Immunology", HKI Jena |
2013 | Habilitation and Venia legendi in microbiology, Friedrich-Schiller-University Jena |
2007-2013 | Head of the working group "Infection Models" within the department of Microbial Pathogenicity Mechanisms, HKI Jena, Deputy Supervisor |
2007 | Veterinary surgeon specialising in microbiology |
2005-2007 | Research assistant (postdoc) at the Institute for Microbiology, University of Veterinary Medicine, Hanover, within the SFB 587 (immune reaction of the lungs in case of infection and allergy, project A4) |
2002-2005 | PhD studies at the University of Veterinary Medicine, Hanover, project: "molecular mechanisms of the adaptation of Actinobacillus pleuropneumoniae to the respiratory tract of pigs" (DFG Research Training Group 745: Mucosal host-pathogen-interaction), PhD degree summa cum laude |
2001 | Veterinary license |
1995-2001 | Studies in veterinary medicine in Hanover and Pretoria, South Africa |
Awards · Appointments · Scientific Activities
since 2013 | Note taker within the specialist group "eukaryotic pathogens", Deutsche Gesellschaft für Hygiene und Mikrobiologie (DGHM) |
2013 | Co-organiser FEBS Advanced Practical Course "state-of-the-art infection models for human pathogenic fungi" |
since 2012 | Academic editor for PLoS One and Medical Mycology Case Reports |
2010-2013 | Deputy member of the advisory panel in accordance with § 15 clause 1 Animal Welfare Act, Thuringia |
2007 | Partial fellowship for taking part in the course molecular mycology: current approaches to fungal pathogenesis, Woods Hole, USA |
2005 | Award in veterinary medicine from the Kurt-Alten-Foundation for the best PhD-thesis |
2001-2004 | Fellow at the DFG’s research training group 745 |
2000 | Full fellowship (The Wellcome Trust) at the summer school: fundamentals of veterinary science, University of Cambridge, UK |
1998 | Awards from the H. Wilhelm Schaumann Stiftung zu Hamburg for the best student achievements |
1995-2001 | Fellow at the Studienstiftung des deutschen Volkes |
Publications
(2012)
The novel Candida albicans transporter Dur31 Is a multi-stage pathogenicity factor.
PLOS Pathog 8(3),
e1002592.
(2012)
Small but crucial: the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans.
PLOS One 7(6),
e38584.
(2012)
The two-component sensor kinase TcsC and its role in stress resistance of the human-pathogenic mold Aspergillus fumigatus.
PLOS One 7(6),
e38262-e38262.
(2012)
Direct analysis and identification of pathogenic Lichtheimia species by matrix-assisted laser desorption ionization-time of flight analyzer-mediated mass spectrometry.
J Clin Microbiol 50(2),
419-427.
(2012)
Lichtheimia species exhibit differences in virulence potential.
PLOS One 7(7),
e40908.
(2012)
Persistence versus escape: Aspergillus terreus and Aspergillus fumigatus employ different strategies during interactions with macrophages.
PLOS One 7(2),
e31223-e31223.
(2012)
Murine infection models for Aspergillus terreus pulmonary aspergillosis reveal long-term persistence of conidia and liver degeneration.
J Infect Dis 205(8),
1268-1277.
(2011)
Detection of precursor lesions of pancreatic adenocarcinoma in PET-CT in a genetically engineered mouse model of pancreatic cancer.
Neoplasia 13(2),
180-186.
(2011)
Pathogenesis of Candida albicans infections in the alternative chorio-allantoic membrane chicken embryo model resembles systemic murine infections.
PLOS One 6(5),
e19741-e19741.