Curriculum vitae

Main Research Areas
  • Immunology and infection biology of pathogenic fungi
  • In vivo and ex vivo infection models
  • Mucosal pathogen-host-interaction
Professional Career
since 2014 Professor for Microbial Immunology, FSU Jena
since 2013 Head of the research group "Microbial Immunology", HKI Jena
2013 Habilitation and Venia legendi in microbiology, Friedrich-Schiller-University Jena
2007-2013 Head of the working group "Infection Models" within the department of Microbial Pathogenicity Mechanisms, HKI Jena, Deputy Supervisor
2007 Veterinary surgeon specialising in microbiology
2005-2007 Research assistant (postdoc) at the Institute for Microbiology, University of Veterinary Medicine, Hanover, within the SFB 587 (immune reaction of the lungs in case of infection and allergy, project A4)
2002-2005 PhD studies at the University of Veterinary Medicine, Hanover, project: "molecular mechanisms of the adaptation of Actinobacillus pleuropneumoniae to the respiratory tract of pigs" (DFG Research Training Group 745: Mucosal host-pathogen-interaction), PhD degree summa cum laude
2001 Veterinary license
1995-2001 Studies in veterinary medicine in Hanover and Pretoria, South Africa
Awards · Appointments · Scientific Activities
since 2013 Note taker within the specialist group "eukaryotic pathogens", Deutsche Gesellschaft für Hygiene und Mikrobiologie (DGHM)
2013 Co-organiser FEBS Advanced Practical Course "state-of-the-art infection models for human pathogenic fungi"
since 2012 Academic editor for PLoS One and Medical Mycology Case Reports
2010-2013 Deputy member of the advisory panel in accordance with § 15 clause 1 Animal Welfare Act, Thuringia
2007 Partial fellowship for taking part in the course molecular mycology: current approaches to fungal pathogenesis, Woods Hole, USA
2005 Award in veterinary medicine from the Kurt-Alten-Foundation for the best PhD-thesis
2001-2004 Fellow at the DFG’s research training group 745
2000 Full fellowship (The Wellcome Trust) at the summer school: fundamentals of veterinary science, University of Cambridge, UK
1998 Awards from the H. Wilhelm Schaumann Stiftung zu Hamburg for the best student achievements
1995-2001 Fellow at the Studienstiftung des deutschen Volkes

Publications

Maurer M, Gresnigt MS, Last A, Wollny T, Berlinghof F, Pospich R, Cseresnyes Z, Medyukhina A, Graf K, Gröger M, Raasch M, Siwczak F, Nietzsche S, Jacobsen ID, Figge MT, Hube B, Huber O, Mosig AS (2019) A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies. Biomaterials 220, 119396.
Allert S*, Förster TM*, Svensson C-M, Richardson JP, Pawlik T, Hebecker B, Rudolphi S, Juraschitz M, Schaller M, Blagojevic M, Morschhäuser J, Figge MT, Jacobsen ID, Naglik JR, Kasper L, Mogavero S, Hube B; *authors contributed equally (2018) Candida albicans-induced epithelial damage mediates translocation through intestinal barriers. mBio 9(3), e00915.
Beyer R, Jandric Z, Zutz C, Gregori C, Willinger B, Jacobsen ID, Kovarik P, Strauss J, Schüller C (2018) Competition of Candida glabrata against Lactobacillus is Hog1 dependent. Cell Microbiol 20(12), e12943.
Conrad T*, Kniemeyer O, Henkel SG, Krüger T, Mattern DJ, Valiante V, Guthke R, Jacobsen ID, Brakhage AA, Vlaic S, Linde J (2018) Module-detection approaches for the integration of multilevel omics data highlight the comprehensive response of Aspergillus fumigatus to caspofungin. BMC Syst Biol 12(1), 88.
de Assis LJ, Manfiolli A, Mattos E, Fabri JHTM, Malavazi I, Jacobsen ID, Brock M, Cramer RA, Thammahong A, Hagiwara D, Ries LNA, Goldman GH (2018) Protein kinase a and high-osmolarity glycerol response pathways cooperatively control cell wall carbohydrate mobilization in Aspergillus fumigatus. mBio 9(6), e01952-18.
Desai PR, Lengeler K, Kapitan M, Janßen SM, Alepuz P, Jacobsen ID, Ernst JF (2018) The 5' untranslated region of the EFG1 transcript promotes its translation to regulate hyphal morphogenesis in Candida albicans. mSphere 3(4), e00280-18.
Eberl C, Speth C, Jacobsen ID, Hermann M, Hagleitner M, Deshmukh H, Ammann CG, Lass-Flörl C, Rambach G (2018) Candida: Platelet interaction and platelet activity in vitro. J Innate Immun 11(1), 52-62.
Irmscher S, Döring N, Halder LD, Jo EAH, Kopka I, Dunker C, Jacobsen ID, Luo S, Slevogt H, Lorkowski S, Beyersdorf N, Zipfel PF, Skerka C (2018) Kallikrein cleaves C3 and activates complement. J Innate Immun 10(2), 94-105.
Kapitan M, Niemiec MJ, Steimle A, Frick JS, Jacobsen ID (2018) Fungi as part of the microbiota and interactions with intestinal bacteria. In: Curr Top Microbiol Immunol (ed.) Current Topics in Microbiology and Immunology 422, pp. 265-301. Springer, Berlin, Heidelberg. (Review)
Luo S, Dasari P, Reiher N, Hartmann A, Jacksch S, Wende E, Barz D, Niemiec MJ, Jacobsen I, Beyersdorf N, Hünig T, Klos A, Skerka C, Zipfel PF (2018) The secreted Candida albicans protein Pra1 disrupts host defense by broadly targeting and blocking complement C3 and C3 activation fragments. Mol Immunol 93, 266-277.