Prof. Dr. Gianni Panagiotou

Microbiome Dynamics · Head +49 3641 532-1759 gianni.panagiotou@leibniz-hki.de

Curriculum vitae

Main Research Areas

Microbiome in health and disease
Systems biology of infectious diseases
Personalized nutrition

Publications

Eisele D^*, Blatzer M, Dietl AM, Binder U, Müller C, Hagen F, Sae-Ong T, Schäuble S, Panagiotou G, Vadehi-Shahandashti R^*, Lass-Flörl C (2025) Aspergillus terreus sectorization: a morphological phenomenon shedding light on amphotericin B resistance mechanism. mBio 16(4), e0392624.

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Herzog E, Ishida K, Scherlach K, Chen X, Bartels B, Niehs SP, Cheaib B, Panagiotou G, Hertweck C (2025) Antibacterial siderophores of Pandoraea pathogens and their impact on the diseased lung microbiota. Angew Chem Int Ed 64(24), e202505714.

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Jentho E, Ademolue TW, Peters-Sengers H, Butler JM, Xu L, Rastogi ST, Kitoko J, Pagnotta S, Drotleff B, Faísca P, Polishchuk V, Mesquita M, Horn P, Metzing UB, Cardoso S, Mithieux G, Bauer M, Chouchane O, Weis S, Panagiotou G, von Loeffelholz C, van der Poll T, Soares MP (2025) A bioenergetic basis for multiorgan dysfunction in sepsis. bioRxiv [Preprint]

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Nikitashina L, Chen X, Radosa L, Li K, Straßburger M, Seelbinder B, Böhnke W, Vielreicher S, Nietzsche S, Heinekamp T, Jacobsen ID, Panagiotou G, Brakhage AA (2025) The murine lung microbiome is disbalanced by the human-pathogenic fungus Aspergillus fumigatus resulting in enrichment of anaerobic bacteria. Cell Rep 44(3), 115442.

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Nychas E^*, Marfil-Sánchez A^*, Chen X, Mirhakkak M, Li H, Jia Q, Xu A, Nielsen HB, Niewdorp M, Loomba R, Ni Y^#, Panagiotou G^# (2025) Discovery of robust and highly specific microbiome signatures of non-alcoholic fatty liver disease. Microbiome 13(1), 10.

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Wang J, Qin Y, Wu Q, Zeng D, Gao X, Wang Q, Li Z, Ni Y^#, Li H, Zhang P, Guo J, Ma W, Maitusun M, Jin X, Chen M, Zhu L, Lu Q, Chen Q, Wu Y, Lin C, Han R, Cheng D, Ni J, Wang X, Yao F, Zhuang J, Xia J, Liu D, Lu Y, Kang P, Yu S, Chen A, Zhang Y, Li Q, Ge W, Long X, Jiang Z, Guan Z, Jin Z, Jin P, Li T, Shu J, Yang J, Wang J, Jiang N, Qian J, Jung Y, Zhang H, Yang Q, Ma L, Wu X, Huang X, Si D, Ren J, Qiao H, Guo Y, Huang Z, Wang W, Deng W, Bi L, Zhao D, Li Y, Lau RWH, Tham YC, Ma X, Ma J, Shen D, Zhang S, Guan H, Zou W, Guo M, Guan X, Yang X, Xu A, Wu J, Panagiotou G, Tse MA, Kim J, Wu E, Thalmann D, Magnenat Thalmann N, Fregni F, Wong TY, Jia W, Zeng R^#, Lim CT^#, Sheng B^#, Li H^# (2025) An adaptive AI-based virtual reality sports system for adolescents with excess body weight: a randomized controlled trial Nature Medicine 31(7), 2255-2268.

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Xiong L, Beyer D, Liu N, Lehmann T, Neugebauer S, Schaeuble S, Sommerfeld O, Ernst P, Svensson CM, Nietzsche S, Scholl S, Bruns T, Gaßler N, Gräler MH, Figge MT, Panagiotou G, Bauer M, Press AT^# (2025) Targeting protein kinase C-α prolongs survival and restores liver function in sepsis: Evidence from preclinical models. Pharmacol Res 212, 107581.

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Xu LL, Heilig L, Bussemer L, Strobel L, Hünniger-Ast K, Kurzai O, Grothey A, Dölken L, Laib Sampaio K, Panagiotou G, Westermann AJ, Einsele H, Wurster S, Schäuble S, Löffler J (2025) Unveiling immune interference: how the dendritic cell response to co-infection with Aspergillus fumigatus is modulated by human cytomegalovirus and its virokine CMVIL-10. mBio [Epub ahead of print]

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Xu LL, McIlroy SE, Ni Y, Guibert I, Chen J, Rocha U, Baker DM^#, Panagiotou G^# (2025) Chemical pollution drives taxonomic and functional shifts in marine sediment 2 microbiome, influencing benthic metazoans. ISME Commun 5(1), ycae141.

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Xu LL, Zhou Z, Schäuble S, Vivas W, Dlubatz K, Bauer M, Weis S, Singer M, Lukaszewski R, Panagiotou G^# (2025) Multi-omics and -organ insights into energy metabolic adaptations in early sepsis onset. Advanced Science [Epub ahead of print]

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