(2015)
Evolution of a Short Route to Strychnine by Using the Samarium Diiodide-Induced Cascade Cyclization as a Key Step
Chemistry - A European Journal 21(23),
8416-8425.
Prof. Dr. Christine Beemelmanns
Chemical Biology of Microbe-Host Interactions · Head +49 3641 532-1525 christine.beemelmanns@leibniz-hki.deCurriculum vitae
Main Research Areas
- Isolation and determination of the structure of signal molecules and antimicrobial natural products
- Characterisation of interactions between microbes and eucaryotes
- Total synthesis of natural products and chemical derivatisation
Professional Career
| since 01/2022 | Professor of Biochemistry of Microbial Metabolism at the University of Leipzig |
| Since 12/2013 | Junior group head at the Leibniz-Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, Jena, chemical biology of microbe-host-interactions |
| 2011-2013 | Postdoc at the Harvard Medical School, Harvard University, supervisor: Prof. J. Clardy, BCMP, Department of Biomolecular Chemistry and Molecular Pharmacology |
| 2010-2011 | Postdoc at the Tokyo Institute of Technology, chemical faculty (Tokyo, Japan) supervisor: Prof. K. Suzuki |
| 2010 | Dr. rer. nat. in chemistry, summa cum laude, Freie Universität Berlin |
| 2007-2010 | PhD dissertation, organic chemistry instructed by Prof. H.-U. Reißig at the Freie Universität Berlin (Germany) |
| 2006-2007 | Research period at the RIKEN, chemistry, in the working group of Prof. M. Sodeoka (Japan) |
| 2001-2006 | Studies in chemistry, diploma at the RWTH Aachen (Germany) |
Awards · Appointments · Scientific Activities
| 2021 | Nachwuchswissenschaftler-Preise für Naturstoffforschung |
| 2020 | Dozentenpreis des Fonds der Chemischen Industrie |
| 2020 | Visiting Professor in Madison Wisconsin USA |
| 2019-2024 | ERC Starting GRant MORPHEUS |
| 2014-2015 | Postdoc fellowship from the Daimler and Benz Foundation and the Reinhard Frank Foundation |
| Since 2014 | Membership VAAM, FEMS and IUMS |
| Since 2014 | Membership Dechema |
| Since 2014 | Membership National Research Foundation of Korea |
| 2011-2013 | Postdoc fellowship from the Leopoldina Nationale Akademie der Wissenschaften; Postdoc fellowship from the DFG rejected |
| 2011 | Ernst-Reuter-Award of the Freie Universität Berlin; Ernst-Reuter-Gesellschaft der Freunde, Förderer und Ehemaligen der Freien Universität Berlin (Berlin, Germany) |
| 2010-2011 | Postdoc fellowship from the DAAD |
| Since 2010 | Member of the commission, Studienstiftung des deutschen Volkes |
| 2007-2010 | Networking fellowship for doctoral researchers at the Studienstiftung des deutschen Volkes |
| 2007-2009 | Doctoral fellowship funded by the Verband Chemischen Industrie (VCI) |
| 2006 | Springorum commemorative coin from the RWTH Aachen (Aachen, Germany) |
| 2006 | Procter and Gamble award, expert group chemistry at the RWTH Aachen |
| 2006-2007 | RIKEN fellowship from the Studienstiftung des deutschen Volkes |
| 2004-2006 | Studies in chemistry: fellowship from the Studienstiftung des deutschen Volkes |
| Since 2003 | Member of the GDCH |
| 2003 | Chemical award from the faculty for mathematics, informatics, natural sciences, RWTH Aachen |
| 2003 | Schöneborn award from the Gesellschaft der Freunde und Förderer der RWTH Aachen e.V., RWTH Aachen (Aachen, Germany) |
Publications
(2015)
Strychnine as Target - Samarium Diiodide as Tool - A Personal Story
The Chemical Record 15(5),
872-885.
(2015)
A new antibacterial octaketide and cytotoxic phenylethanoid glycosides from Pogostemon cablin (Blanco) Benth
Bioorg. Med. Chem. Lett. 14(25),
2834-2836.
(2015)
Genome Sequences of Three Pseudoalteromonas Strains P1-8, P1-11 and P1-30 Isolated from the Marine Hydroid Hydractinia echinata
Genome Announc. 3(6),
e01380-15.
(2015)
Draft Genome Sequences of Six Pseudoalteromonas sp. Strains P1-7a, P1-9, P1-13-1a, P1-16-1b, P1-25 and P1-26, which Induce Larval Settlement and Metamorphosis in Hydractinia echinata
Genome Announc. 3(6),
e01477-15.
(2014)
Synthesis of the rosette-inducing factor RIF-1 and analogs.
J. Am. Chem. Soc. 136(29),
10210-10213.
(2014)
Naphthalenones and isocoumarins from a Costa Rican fungus Xylariaceae sp. CR1546C
Journal of Chemical Research 38(12),
722-725.
(2014)
Natalamycin A, an ansamycin from a termite-associated Streptomyces sp
Chem. Sci. 5(11),
4333-4338.
(2014)
Bacterial symbionts in agricultural systems provide a strategic source for antibiotic discovery.
J Antibiot (Tokyo) 67(1),
53-58.
(2013)
Towards the core structure of Strychnos alkaloids using samarium diiodide-induced reactions of indole derivatives.
Chemistry 19(52),
17801-17808.
