(2022)
Small extracellular vesicles from peripheral blood of aged mice pass the blood-brain barrier and induce glial cell activation.
Cells 11(4),
625.
Prof. Dr. Sebastian Weis
Translational Infection Medicine · Head +49 3641 532-1771 Sebastian.Weis@med.uni-jena.deCurriculum vitae
Main Research Areas
- Disease Tolerance to Infection
- Innate Immunity
- Heme Metabolism
- Metabolic Adaptation
- Sepsis
- Staphylococcus aureus Bacteremia
Professional Career
| since 2021 | W3 Professor for "Translational Infection Research", FSU Jena |
| since 2021 | Member of the Ethics Committee, FSU Jena |
| 2021 | Call W2 Professorship "Inflammation and Haematopoiesis", TU Dresden, declined |
| 2019 | Senior Physician, Institute for Infectious Medicine and Hospital Hygiene |
| 2019 | Call W3 Professorship "Clinical Infectious Disease", Tübingen, declined |
| 2019 | Call W2 professorship "Clinical Infectiology and Immunology", UKE Hamburg, declined |
| seit 2019 | Subgroup Coordinator, Cluster of Excellence "Balance of the Microverse", FSU Jena |
| 2018 | Subspecialisation in Clinical Infectious Disease |
| 2018 | Member of the Board IFB Center for Sepsis Control and Care, FSU Jena |
| 2018 | Member Cluster of Excellence "Balance of the Microverse”, FSU Jena |
| 2018 | Examiner 3rd State Examination in Human Medicine |
| 2017 | Habilitation and Venia legendi Internal Medicine, FSU Jena |
| 2015 | Training in Clinical Infectiology with Prof. M.W. Pletz, JUH |
| 2012-2015 | Postdoctoral Fellow, Instituto Gulbenkian de Ciência (IGC), Portugal |
| 2012 | Specialist Examination in Internal Medicine |
| 2007-2012 | Specialist Training in Internal Medicine with Prof. J.Mössner, Leipzig University Hospital and Prof. G.Hindricks, Heart Center Leipzig |
| 2008 | Medical Dissertation “On Paraenzymatic Functions of Heme Oxygenease-1” (summa cum laude), University of Leipzig, Germany |
| 2007 | Visiting Researcher, MRC Fajara, The Gambia, West-Afrika |
| 2006 | Approbation/Physician's license |
| 2005 | Clinical Elective, Medical Research Council, Fajara, The Gambia |
| 2002-2003 | Visiting Researcher, Dept. of Pediatrics, Stanford University, USA |
| 1999-2006 | Studies of Medicine, University of Leipzig, Germany; Practical Year: Children´s Hospital of Philadelphia, USA and St. Georg Hospital, Leipzig, Germany |
Awards · Appointments · Scientific Activities
| 2018 | Winner Science Slam, KIT 2018 |
| 2018 | Best Oral Presentation Award, 10th Meeting of HO, Seoul |
| 2017 | Hugo-Schottmüller Award of the German Sepsis Society |
| 2017 | Best Abstract Award, International Sepsis Forum |
| 2012-2014 | DFG Fellowship for Research Abroad |
| 2010 | Formula 1 Research Fellowship, University of Leipzig |
| 2008 | Doberentz Prize of the University of Leipzig for Outstanding Dissertations |
Publications
(2022)
Impact of the COVID-19 pandemic on influenza and RSV antibody titres in the community - a prospective cohort study in Neustadt Thuringia/Germany.
Eur Respir J 60(5),
2200947.
(2022)
A hypometabolic defense strategy against malaria.
Cell Metab 34(8),
1183-1200.e12.
(2022)
Behandlung von Staphylococcus-aureus-Blutstrominfektionen.
Z Pneumologie 19,
343-358.
(2022)
Tidy up - The unfolded protein response in sepsis.
Front Immunol 13,
980680.
(Review)
(2022)
Effect of automated telephone infectious disease consultations to nonacademic hospitals on 30-day mortality among patients with Staphylococcus aureus Bacteremia: The SUPPORT cluster randomized clinical trial.
JAMA Netw Open 5(6),
e2218515.
(2021)
Tetracycline antibiotics induce Host-dependent disease tolerance to infection.
Immunity 54(1),
53-67.e7.
(2021)
Trained immunity, tolerance, priming and differentiation: distinct immunological processes.
Nat Immunol 22(1),
2-6.
(2021)
Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme.
Proc Natl Acad Sci U S A 118(42),
e2102698118.
(2021)
DAMPs and innate immune training.
Front Immunol 12,
699563.
(Review)
