Curriculum vitae

Professional Career
Since 2022 Postdoctoral Researcher, Jena University Hospital and Leibniz Institute for Natural Product Research and Infection Biology—Hans Knöll Institute; Head: Prof. Dr. Sebastian Weis.
2021 PhD, Double degree in Chemical biology and Drug Discovery, Grenoble University (FR) and Utrecht University (NL), "Characterization of lectins from emerging opportunistic fungi and identification of novel lectins from fungal extracts"
2021 Recombinant Protein Engineer, Center for Research on Plant Macromolecules (FR)
2017-2018 Research Assistant, Autonomous University of Querètaro
2015-2017 MSc, Biotechnology of plants, Center for Research and Advanced Studies of the National Polytechnic Institute, "Production of a recombinant lectin of tépari bean (Phaseolus acutifolius) with cytotoxic effect on colon cancer cells"
2009-2014 BSc, Biotechnology, Autonomous University of Querètaro, "Rizo-secretion of a recombinant lectin with biological activity through the genetic manipulation of bean tépari (Phaseolus acutifolius)"
Awards · Appointments · Scientific Activities

Patents:

1. Patent of standard invention "Recombinant bioactive bean lectins" with registration foil 390689 and expiration date of May 21. 2035. Submitted on May 21, 2015. Granted on March 15 by the Mexican Institute of Industrial Property (IMPI)
2. Submitted patent of standard invention with registration foil MX/a/2018/058313. Submitted on August 2, 2018 at the Mexican Institute of Industrial Property (IMPI)
2023 Nominated by European Commission to attend 72nd Lindau Nobel Laureate Meeting of Ohysiology and Medicine, DE  
2019 Poster Prize Winner at the congress of "Chemystry and Innovating Science", NL
2018 Semifinalist of "The international GIST Tech-I Competition", TR

Publications

Martínez-Alarcón D, Balloy V, Bouchara JP, Pieters RJ, Varrot A (2021) Biochemical and structural studies of target lectin SapL1 from the emerging opportunistic microfungus Scedosporium apiospermum. Sci Rep 11(1), 16109.
Palmerín-Carreño D, Martínez-Alarcón D, Dena-Beltrán J L, Vega-Rojas LJ, Blanco-Labra A, Escobedo-Reyes A, Tersa García-Gasca T* (2021) Optimization of a Recombinant Lectin Production in Pichia pastoris Using Crude Glycerol in a Fed-Batch System Processes 2021, 9(5), 876; https://doi.org/10.3390/pr9050876 [In press]
Martínez-Alarcón D, Varrot A, Fitches E, Gatehouse JA, Cao M, Pyati P, Blanco-Labra A, Garcia-Gasca T (2020) Recombinant Lectin from Tepary Bean (Phaseolus acutifolius) with Specific Recognition for Cancer-Associated Glycans: Production, Structural Characterization, and Target Identification. Biomolecules 10(4),
Martínez-Alarcón D, Mora-Avilés A, Espinoza-Núñez A, Serrano Jamaica LM, Cruz-Hernández A, Rodríguez-Torres A, Castro-Guillen JL, Blanco-Labra A, García-Gasca T (2019) Rhizosecretion of a cisgenic lectin by genetic manipulation of Tepary bean plants (Phaseolus acutifolius). J Biotechnol 306S, 100013.
Martínez-Alarcón D, Blanco-Labra A, García-Gasca T (2018) Expression of Lectins in Heterologous Systems. Int J Mol Sci 19(2),