2-Methyl-2-(4-nitro-phen-oxy)propanoic acid.

Navarrete-Vázquez G, Torres-Gómez H, Hidalgo-Figueroa S, Tlahuext H (2008) 2-Methyl-2-(4-nitro-phen-oxy)propanoic acid. Acta Crystallogr Sect E Struct Rep Online 64(Pt 12), o2261.

Abstract

The title compound, C(10)H(11)NO(5), is of inter-est with respect to its anti-dyslipidemic activity. It was prepared by reaction of 4-nitro-phenol with ethyl 2-bromo-2-methyl-propionate followed by ethyl ester hydrolysis. In the crystal, mol-ecules are linked into centrosymmetric dimers by inter-molecular O-H⋯O hydrogen bonds and the dimers are connected into chains by weak C-H⋯O inter-actions. The packing is further stabilized by offset π-π inter-actions between adjacent benzene rings with a centroid-centroid distance of 3.8643 (17) Å.

Leibniz-HKI-Authors

Héctor Torres-Gomez

Identifier

doi: 10.1107/S1600536808035411

PMID: 21581242