Transfer Group Antiinfectives

Alt S, Haggstrom D, Kessmann H, Kloss F, Schneider CE, Jäger T, Schwede T, Brakhage A, Dehio C (2022) INCATE: a partnership to boost the antibiotic pipeline. Nat Rev Drug Discov 21(9), 621-622. (Review)

Bernal FA, Hammann P, Kloss F (2022) Natural products in antibiotic development: is the success story over? Curr Opin Biotechnol 78, 102783. (Review)

Bitar L, Uphaus T, Thalman C, Muthuraman M, Gyr L, Ji H, Domingues M, Endle H, Groppa S, Steffen F, Koirala N, Fan W, Ibanez L, Heitsch L, Cruchaga C, Lee JM, Kloss F, Bittner S, Nitsch R, Zipp F, Vogt J (2022) Inhibition of the enzyme autotaxin reduces cortical excitability and ameliorates the outcome in stroke. Sci Transl Med 14(641), eabk0135.

Endle H, Horta G, Stutz B, Muthuraman M, Tegeder I, Schreiber Y, Snodgrass IF, Gurke R, Liu ZW, Sestan-Pesa M, Radyushkin K, Streu N, Fan W, Baumgart J, Li Y, Kloss F, Groppa S, Opel N, Dannlowski U, Grabe HJ, Zipp F, Rácz B, Horvath TL, Nitsch R, Vogt J (2022) AgRP neurons control feeding behaviour at cortical synapses via peripherally derived lysophospholipids. Nat Metab 4(6), 683-692.

Haensch V, Neuwirth T, Bergner A, Bruhnke J, Kloss F, Hertweck C (2022) Sustainable and highly controlled aryl couplings revealed by systematic assessment of photoactivatable linkers. Chem Sci 13(19), 5680-5686.

Riabova O, Egorova A, Lepioshkin A, Li Y, Voigt K, Kloss F, Makarov V (2022) Thienol[2,3-d]pyrimidine-core compounds show activity against clinically relevant gram-positive bacteria. ChemMedChem 17(17), e202200207.

Schieferdecker S, Bernal FA, Wojtas KP, Keiff F, Li Y, Dahse HM, Kloss F (2022) Development of predictive classification models for whole cell antimycobacterial activity of benzothiazinones. J Med Chem 65(9), 6748-6763.

Stein J, Schlosser N, Bardl B, Peschel G, Meyer F, Kloss F, Rosenbaum MA, Regestein L (2022) Scalable downstream method for the cyclic lipopetidejagaricin. Eng Life Sci 22(12), 811-817.

Böttcher S, Hartung S, Meyer F, Rummler S, Voigt K, Walther G, Hochhaus A, von Lilienfeld-Toal M, Jahreis S (2021) Human mucosal-associated invariant T cells respond to Mucorales species in a MR1-dependent manner. Med Mycol 59(5), 505-509.

Brantl V, Boysen JM, Yap A, Golubtsov E, Ruf D, Heinekamp T, Straßburger M, Dichtl K, Haas H, Hillmann F, Wagener J (2021) Peroxiredoxin Asp f3 is essential for Aspergillus fumigatus to overcome iron limitation during infection. mBio 12(4), e0097621.