Transfer Group Anti-infectives

Kloss F, Gerbach S (2018) Hürden und Aussichten neuer antimikrobieller Konzepte in Forschung und Entwicklung. [Obstacles and perspectives of new antimicrobial concepts within research and development]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 61(5), 595-605. (Review)

Kloss F, Neuwirth T, Haensch VG, Hertweck C (2018) Metal-free synthesis of pharmaceutically important biaryls by photosplicing. Angew Chem Int Ed 57(44), 14476-14481.

Long N, Orasch T, Zhang S, Gao L, Xu X, Hortschansky P, Ye J, Zhang F, Xu K, Gsaller F, Straßburger M, Binder U, Heinekamp T, Brakhage AA, Haas H, Lu L (2018) The Zn2Cys6-type transcription factor LeuB cross-links regulation of leucine biosynthesis and iron acquisition in Aspergillus fumigatus. PLOS Genet 14(10), e1007762.

Voltersen V, Blango MG, Herrmann S, Schmidt F, Heinekamp T, Strassburger M, Krüger T, Bacher P, Lother J, Weiss E, Hünniger K, Liu H, Hortschansky P, Scheffold A, Loeffler J, Krappmann S, Nietzsche S, Kurzai O, Einsele H, Kniemeyer O, Filler S, Reichard U, Brakhage AA (2018) Proteome analysis reveals the conidial surface protein CcpA essential for virulence of the pathogenic fungus Aspergillus fumigatus. mBio 9(5), e01557-18.

Kloss F, Krchnak V, Krchnakova A, Schieferdecker S, Dreisbach J, Krone V, Möllmann U, Hoelscher M, Miller MJ (2017) In Vivo Dearomatization of the Potent Antituberculosis Agent BTZ043 via Meisenheimer Complex Formation. Angew Chem Int Ed 56(8), 2187-2191.

Hillmann F, Bagramyan K, Straßburger M, Heinekamp T, Hong TB, Bzymek KP, Williams JC, Brakhage AA, Kalkum M (2016) The crystal structure of peroxiredoxin Asp f3 provides mechanistic insight into oxidative stress resistance and virulence of Aspergillus fumigatus. Sci Rep 6, 33396.

Kniemeyer O, Ebel F, Krüger T, Bacher P, Scheffold A, Luo T, Strassburger M, Brakhage AA (2016) Immunoproteomics of Aspergillus for the development of biomarkers and immunotherapies. Proteomics Clin Appl 10(9-10), 910-921. (Review)

Schieferdecker S, Nett M (2016) A fast and efficient method for the preparation of the 5-lipoxygenase inhibitor myxochelin A. Tetrahedron Lett 57, 1359-1360.

Valiante V, Baldin C, Hortschansky P, Jain R, Thywißen A, Straßburger M, Shelest E, Heinekamp T, Brakhage AA (2016) The Aspergillus fumigatus conidial melanin production is regulated by the bifunctional bHLH DevR and MADS-box RlmA transcription factors. Mol Microbiol 102(2), 321-335.

Bauer JS, Ghequire MG, Nett M, Josten M, Sahl HG, De Mot R, Gross H (2015) Biosynthetic origin of the antibiotic pseudopyronines A and B in Pseudomonas putida BW11M1. ChemBioChem 16, 2491-2497.