Publications

Herisse M, Ishida K, Staiger-Creed J, Judd L, Williams SJ, Howden BP, Stinear TP, Dahse HM, Voigt K, Hertweck C, Pidot SJ (2023) Discovery and biosynthesis of the cytotoxic polyene terpenomycin in human pathogenic Nocardia. ACS Chem Biol 18(8), 1872-1879.
Trottmann F, Fiedler J, Ishida K, Ishida-Ito M, Little RF, Hertweck C (2023) Bacterial pathogen channels medium-sized fatty acids into malleicyprol biosynthesis. ACS Chem Biol 18(7), 1557-1563.
Bredy F, Ishida K, Hertweck C (2022) A type III polyketide synthase specific for sporulating negativicutes is responsible for alkylpyrone biosynthesis. ChemBioChem 23(21), e202200431.
Kim HJ, Ishida K, Hertweck C (2022) Thiotemplated biosynthesis of bacterial polyyne fatty acids by a designated desaturase triad. ChemBioChem 23(21), e202200430.
Kim HJ, Ishida K, Ishida-Ito M, Hertweck C (2022) Sequential allylic alcohol formation by a multifunctional cytochrome P450 monooxygenase with rare redox partners. Angew Chem Int Ed 61(26), e202203264.
Krumbholz J, Ishida K, Baunach M, Teikari JE, Rose MM, Sasso S, Hertweck C, Dittmann E (2022) Deciphering chemical mediators regulating specialized metabolism in a symbiotic cyanobacterium. Angew Chem Int Ed 61(26), e202204545.
Trottmann F, Ishida K, Ishida-Ito M, Kries H, Groll M, Hertweck C (2022) Pathogenic bacteria remodel central metabolic enzyme to build a cyclopropanol warhead. Nat Chem 14(8), 884-890.
Ishida K, Shabuer G, Schieferdecker S, Pidot SJ, Stinear TP, Knuepfer U, Cyrulies M, Hertweck C (2020) Oak-associated negativicute equipped with ancestral aromatic polyketide synthase produces antimycobacterial dendrubins. Chem Eur J 26(58), 13147-13151.
Neuwirth T, Letzel AC, Tank C, Ishida K, Cyrulies M, Schmölz L, Lorkowski S, Hertweck C (2020) Induced production, synthesis and immunomodulatory action of clostrisulfone, a diarylsulfone from Clostridium acetobutylicum. Chemistry 26(68), 15855-15858.
Niehs SP, Kumpfmüller J, Dose B, Little RF, Ishida K, Florez LV, Kaltenpoth M, Hertweck C (2020) Insect-associated bacteria assemble the antifungal butenolide gladiofungin by non-canonical polyketide chain termination. Angew Chem Int Ed 59(51), 23122-23126.