(2020)
Sulfonium acids loaded onto an unusual thiotemplate assembly line construct the cyclopropanol warhead of a Burkholderia virulence factor.
Angew Chem Int Ed 59(32),
13511-13515.
Publications
(2019)
Genome mining and heterologous expression reveal two distinct families of lasso peptides highly conserved in endofungal bacteria.
ACS Chem Biol 15(5),
1169-1176.
(2019)
Identification and mobilization of a cryptic antibiotic biosynthesis gene locus from a human-pathogenic nocardia isolate.
ACS Chem Biol 15(5),
1161-1168.
(2019)
Genomics-driven discovery of NO-donating diazeniumdiolate siderophores in diverse plant-associated bacteria.
Angew Chem Int Ed 58(37),
13024-13029.
(2019)
Unique biosynthetic pathway in bloom-forming cyanobacterial genus Microcystis jointly assembles cytotoxic aeruginoguanidines and microguanidines.
ACS Chem Biol 14(1),
67-75.
(2019)
Loss of single domain function in modular assembly line alters size and shape of complex polyketide.
Angew Chem Int Ed 58(50),
18252-18256.
(2019)
Emulating evolutionary processes to morph aureothin-type modular polyketide synthases and associated oxygenases.
Nat Commun 10(1),
3918.
(2019)
Biosynthesis of diverse antimicrobial and antiproliferative acyloins in anaerobic bacteria.
ACS Chem Biol 14(7),
1490-1497.
(2019)
A pair of bacterial siderophores releases and traps an intercellular signal molecule: An unusual case of natural nitrone bioconjugation.
Angew Chem Int Ed 58(1),
200-204.
(2019)
Cyclopropanol warhead in malleicyprol confers virulence of human- and animal-pathogenic Burkholderia species.
Angew Chem Int Ed 58(40),
14129-14133.
