Prof. Dr. Gianni Panagiotou

Microbiome Dynamics · Head +49 3641 532-1759 gianni.panagiotou@leibniz-hki.de

Curriculum vitae

Main Research Areas

Microbiome in health and disease
Systems biology of infectious diseases
Personalized nutrition

Publications

Janevska S^*^#, Gómez-Gil L^*, Sae-Ong T, Farooq U, Studt-Reinhold L, López-Berges MS, Panagiotou G, Rep M, Di Pietro A (2026) Facultative heterochromatin mediated by core and accessory chromosome-encoded H3K27-specific methyltransferases controls virulence in a fungal phytopathogen. Nucleic Acids Res 54(1), gkaf1441.

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Perie L, Herr SM, Ghebreslassie T, Wulf S, Löschmann I, Sekulic A, Suwandi A, Maier AKB, Rowlin L, Jungnickel B, Schäuble S, Panagiotou G, Strauß O, Wiech T, Zipfel PF, Zipfel SLH, Skerka C (2026) Deletion of the mouse homolog of human FHR1 (muFHR1) alleviates Atherosclerosis in ApoE-/- mice. Int J Med Sci 23(2), 585-599.

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Shehata A^*, Schäuble S^*, Martin R, Aldejohann AM, Panagiotou G, Kurzai O, Hünniger-Ast K (2026) Caspofungin enhances antifungal immunity in human blood through transcriptional reprogramming. microLife [Accepted]

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Bruch A^*, Lazarova V^*, Berg M, Krueger T, Schaeuble S, Kelani AA, Mertens B, Lehenberger P, Kniemeyer O, Kaiser S, Panagiotou G, Gsaller F, Blango MG (2025) tRNA hypomodification facilitates 5-fluorocytosine resistance via cross-pathway control system activation in Aspergillus fumigatus Nucleic Acids Res 53(3), gkae1205.

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Eisele D^*, Blatzer M, Dietl AM, Binder U, Müller C, Hagen F, Sae-Ong T, Schäuble S, Panagiotou G, Vadehi-Shahandashti R^*, Lass-Flörl C (2025) Aspergillus terreus sectorization: a morphological phenomenon shedding light on amphotericin B resistance mechanism. mBio 16(4), e0392624.

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Guerra J, Jentho E, Schäuble S, Scicluna B P, Vivas W, Martínez-Alarcón D, Groth M, King E, Röstel F, Hirth G, Soares M P, WiechT, Panagiotou G, Bauer M, Hoerr V, Weis S^# (2025) Control of renal central carbon metabolism by heme oxygenase-1. iScience 29(1), 114370.

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Heilig L, Bussemer L, Strobel L, Hünniger-Ast K, Kurzai O, Grothey A, Dölken L, Laib Sampaio K, Panagiotou G, Westermann AJ, Einsele H, Wurster S, Schäuble S, Löffler J (2025) Unveiling immune interference: how the dendritic cell response to co-infection with Aspergillus fumigatus is modulated by human cytomegalovirus and its virokine CMVIL-10. mBio 16(11), e0154125.

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Herzog E, Ishida K, Scherlach K, Chen X, Bartels B, Niehs SP, Cheaib B, Panagiotou G, Hertweck C (2025) Antibacterial siderophores of Pandoraea pathogens and their impact on the diseased lung microbiota. Angew Chem Int Ed 64(24), e202505714.

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Jentho E, Ademolue TW, Peters-Sengers H, Butler JM, Xu L, Rastogi ST, Kitoko J, Pagnotta S, Drotleff B, Faísca P, Polishchuk V, Mesquita M, Horn P, Metzing UB, Cardoso S, Mithieux G, Bauer M, Chouchane O, Weis S, Panagiotou G, von Loeffelholz C, van der Poll T, Soares MP (2025) A bioenergetic basis for multiorgan dysfunction in sepsis. bioRxiv [Preprint]

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Long X, Wang H, Lu Y, Gao X, Xiao Y, Zhang M, Guo J, Yang J, Zhang R, Li Q, Zhou G, Yang R, Chen F, Wu Q, Sun L, Chu C, Zhu X, Wu Z, Ren Q, You C, Liu Z, Li Q, Liu D, Cheng D, Kang P, Chen A, Wu Q, Fang Q, Wei L, Zhang L, Li J, Panagiotou G, Jia W^#, Zeng R, Ni Y^#, Chen L, Li H^# (2025) Interindividual variability in gut microbiome mediates the efficacy of resistant starch on MASLD. Cell Metab 37(12), 2342-2361.e9..

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