Mikrobielle Pathogenitätsmechanismen

Alonso-Roman R, Mosig AS, Figge MT, Papenfort K, Eggeling C, Schacher FH, Hube B^#, Gresnigt MS (2024) Organ-on-chip models for infectious disease research. Nat Microbiol 9(4), 891-904.

Böttcher B, Kienast SD, Leufken J, Eggers C, Sharma P, Leufken CM, Morgner B, Drexler HCA, Schulz D, Allert S, Jacobsen ID, Vylkova S, Leidel SA, Brunke S^# (2024) A highly conserved tRNA modification contributes to C. albicans filamentation and virulence. Microbiol Spectr 12(5), e0425522.

Chamas A, Svensson CM, Maneira C, Sporniak M, Figge MT, Lackner G (2024) Engineering adhesion of the probiotic strain Escherichia coli nissle to the fungal pathogen Candida albicans. ACS Synth Biol ,

Jaeger M, Dietschmann A, Austermeier S, Dinçer S, Porschitz P, Vornholz L, Maas RJA, Sprenkeler EGG, Ruland J, Wirtz S, Azam T, Joosten LAB, Hube B, Netea MG, Dinarello CA, Gresnigt MS (2024) Alpha1-antitrypsin impacts innate host-pathogen interactions with Candida albicans by stimulating fungal filamentation. Virulence 15(1), 2333367.

Kaden T^*, Alonso-Roman R^*, Akbarimoghaddam P^*, Mosig AS, Graf K, Raasch M, Hoffmann B, Figge MT^#, Hube B^#, Gresnigt MS^# (2024) Modeling of intravenous caspofungin administration using an intestine-on-chip reveals altered Candida albicans microcolonies and pathogenicity. Biomaterials 307, 122525.

Katsipoulaki M, Stappers MHT, Malavia-Jones D, Brunke S, Hube B, Gow NAR (2024) Candida albicans and Candida glabrata: global priority pathogens. Microbiol Mol Biol Rev 88(2), e0002123. (Review)

Liang SH, Sircaik S, Dainis J, Kakade P, Penumutchu S, McDonough LD, Chen YH, Frazer C, Schille TB, Allert S, Elshafee O, Hänel M, Mogavero S, Vaishnava S, Cadwell K, Belenky P, Perez JC, Hube B, Ene IV, Bennett RJ (2024) The hyphal-specific toxin candidalysin promotes fungal gut commensalism. Nature 627(8004), 620-627.

Müller R, König A, Groth S, Zarnowski R, Visser C, Handrianz T, Maufrais C, Krüger T, Himmel M, Lee S, Priest EL, Yildirim D, Richardson JP, Blango MG, Bougnoux ME, Kniemeyer O, d'Enfert C, Brakhage AA, Andes DR, Trümper V, Nehls C, Kasper L, Mogavero S, Gutsmann T, Naglik JR, Allert S, Hube B (2024) Secretion of the fungal toxin candidalysin is dependent on conserved precursor peptide sequences. Nat Microbiol 9(3), 669-683.

Schaefer S, Corrigan N, Brunke S, Lenardon MD, Boyer C (2024) Combatting fungal infections: advances in antifungal polymeric nanomaterials. Biomacromolecules 25(9), 5670-5701. (Review)

Schaefer S, Vij R, Sprague JL, Austermeier S, Dinh H, Judzewitsch PR, Müller-Loennies S, Lopes Silva T, Seemann E, Qualmann B, Hertweck C, Scherlach K, Gutsmann T, Cain AK, Corrigan N, Gresnigt MS, Boyer C, Lenardon MD, Brunke S (2024) A synthetic peptide mimic kills Candida albicans and synergistically prevents infection. Nat Commun 15(1), 6818.