Mikrobielle Pathogenitätsmechanismen

Chang TH, Cardona Gloria Y, Hellmann MJ, Richardo T, Greve CL, Le Roy D, Roger T, Bork F, Bugl S, Jakob J, Sonnberger J, Kasper L, Hube B, Pusch S, Gow NAR, Sørlie M, Tøndervik A, Moerschbacher BM, Weber ANR (2025) Transkingdom mechanism of MAMP generation by chitotriosidase feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing. Front Immunol 16, 1497174.

Makambi WK, Chiu VL, Kasper L, Hube B, Karlsson AJ (2025) Role of amino acid substitutions on proteolytic stability of histatin 5 in the presence of secreted aspartyl proteases and salivary proteases. Protein Sci 34(1), e70011.

Maneira C, Chamas A, Lackner G (2025) Engineering Saccharomyces cerevisiae for medical applications. Microb Cell Fact 24(1), 12. (Review)

Rosati D, Valentine M, Bruno M, Pradhan A, Dietschmann A, Jaeger M, Leaves I, van de Veerdonk FL, Joosten LAB, Roy S, Stappers MHT, Gow NAR, Hube B, Brown AJP, Gresnigt MS, Netea MG (2025) Lactic acid in the vaginal milieu modulates the Candida-host interaction. Virulence 16(1), 2451165.

Alonso-Roman R, Mosig AS, Figge MT, Papenfort K, Eggeling C, Schacher FH, Hube B^#, Gresnigt MS (2024) Organ-on-chip models for infectious disease research. Nat Microbiol 9(4), 891-904. (Review)

Böttcher B, Kienast SD, Leufken J, Eggers C, Sharma P, Leufken CM, Morgner B, Drexler HCA, Schulz D, Allert S, Jacobsen ID, Vylkova S, Leidel SA, Brunke S^# (2024) A highly conserved tRNA modification contributes to C. albicans filamentation and virulence. Microbiol Spectr 12(5), e0425522.

Castaño-Cerezo S, Chamas A, Kulyk H, Treitz C, Bellvert F, Tholey A, Galéote V, Camarasa C, Heux S, Garcia-Alles LF, Millard P, Truan G (2024) Combining systems and synthetic biology for in vivo enzymology. EMBO J 43(21), 5169-5185.

Jaeger M, Dietschmann A, Austermeier S, Dinçer S, Porschitz P, Vornholz L, Maas RJA, Sprenkeler EGG, Ruland J, Wirtz S, Azam T, Joosten LAB, Hube B, Netea MG, Dinarello CA, Gresnigt MS (2024) Alpha1-antitrypsin impacts innate host-pathogen interactions with Candida albicans by stimulating fungal filamentation. Virulence 15(1), 2333367.

Kaden T, Alonso-Román R, Stallhofer J, Gresnigt MS, Hube B, Mosig AS (2024) Leveraging organ-on-chip models to investigate host-microbiota dynamics and targeted therapies for inflammatory bowel disease. Adv Healthc Mater , e2402756. (Review)